Critical Care

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Mismatch-based delayed thrombolysis attractive but not yet ready for routine care
[2 December 2009]

Prehospital intranasal cooling after cardiac arrest is feasible and may improve survival
[19 November 2009]

Hypothermia decreases brain injury in hypoxic infants; MRI aids in predicting prognosis
[13 November 2009]

New guidelines on H1N1 influenza urge quicker use of antivirals
[13 November 2009]

Prone positioning may not improve survival duration in patients with acute respiratory distress syndrome
[11 November 2009]

Editor-in-Chief
Jean-Louis Vincent
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Affiliated to the International Symposium on Intensive Care and Emergency Medicine(ISICEM), Brussels, Belgium

Welcome to Critical Care

The online intensive care journal
Editor-in-chief: Jean-Louis Vincent, Brussels, Belgium

Research highlight: 'No advantage' to post-pyloric feeding

Early post-pyloric feeding of mechanically ventilated intensive care patients is no more effective than early gastric feeding in terms of nutritional outcomes or complications such as ventilator associated pneumonia and mortality.

Critical Care 2009, 13:R187

Latest articles

	Commentary Disinfection of the hospital water supply: a hidden risk to dialysis patients Nicholas A Hoenich Critical Care 2009, 13:1007 (1 December 2009) [PDF]

	Commentary Matrix metalloproteinases and their inhibitors: promising novel biomarkers in severe sepsis? Ursula Hoffmann, Martina Brueckmann, Martin Borggrefe Critical Care 2009, 13:1006 (1 December 2009) [PDF]

	Review Clinical review: Post-extubation laryngeal edema and extubation failure in critically ill adult patients Bastiaan HJ Wittekamp, Walther NKA van Mook, Dave HT Tjan, Jan Harm Zwaveling, Dennis CJJ Bergmans Critical Care 2009, 13:233 (1 December 2009) [PDF]

	Research Vestibulo-ocular monitoring as a predictor of outcome after severe traumatic brain injury Hans-Georg Schlosser, Jan-Nikolaus Lindemann, Peter Vajkoczy, Andrew H Clarke Critical Care 2009, 13:R192 (30 November 2009) [Abstract] [Provisional PDF]

	Research Prothrombin complex concentrate in surgical patients: retrospective evaluation of vitamin K antagonist reversal and treatment of severe bleeding Kerstin S Schick, Jan M Fertmann, Karl-Walter Jauch, Johannes N Hoffmann Critical Care 2009, 13:R191 (30 November 2009) [Abstract] [Provisional PDF]

	Research Angiotensin II in experimental hyperdynamic sepsis Li Wan, Christoph Langenberg, Rinaldo Bellomo, Clive N May Critical Care 2009, 13:R190 (30 November 2009) [Abstract] [Provisional PDF]

Open access

All research articles published in Critical Care are open access [more]

Image highlight

Illustrative example of Doppler evaluation of brachial artery peak velocity variation (ΔVpeakbrach) in a responder patient (left) and nonresponder patient (right).

Latest supplements

Volume 13 Suppl 5
Tissue oxygenation (StO₂) in healthy volunteers and critically-ill patients
Research

Volume 13 Suppl 4
Sepsis 2009
Abstracts

Volume 13 Suppl 3
Fifth International Symposium on Intensive Care and Emergency Medicine for Latin America
Abstracts

All articles published in supplements are fully peer reviewed.

Free review

All reviews, commentaries and reports published in Critical Care become free to access 12 months after publication. See below for the latest free review.

Review

Clinical review: Balancing the therapeutic, safety, and economic issues underlying effective antipseudomonal carbapenem use

Thomas G Slama

Critical Care 2008, 12:233 (29 October 2008)

[Abstract][Full text][PDF] [PubMed] [Related articles]

Journal Club Critiques

From the University of Pittsburgh evidence-based medicine journal club

Journal club critique

Are specialized ICUs so special?

Yên-Lan C Nguyen, Eric B Milbrandt

Critical Care 2009, 13:314 (12 October 2009)

[Abstract] [Full Text] [PDF]

Latest comments

Ventilator-associated tracheobronchitis after major heart surgery: a plea for a randomized trial (Saad Nseir, 13Jul2009)
I read with interest the article by Dr. Hortal and colleagues [1]. The authors are to be congratulated for conducting such a large multicentre study on the incidence of and... [read full comment]

Comment on: Hortal JM et al. Critical Care, 13:R80
Sepsis 14 Calculation Worksheet (Christophe Adrie, 11Jun2009)
A calculation worksheet "Sepsis 14" allowing an easy use of the "Model for predicting short-term mortality of severe sepsis" is available on our website: http://www.outcomerea.org/ehtm/sepsis/... [read full comment]

Comment on: Adrie C et al. Critical Care, 13:R72
Possible explainations for a rise in ScvO2 following intubation (Paul Dean, 22May2009)
Dear Sir I read with interest Hernandez et al study into the effect on intubation on ScvO2. As they point out there remains some concern regarding the usefulness of ScvO2.... [read full comment]

Comment on: Hernandez G et al. Critical Care, 13:R63