- Jean-Louis Vincent, Erasme University Hospital
Acid-base abnormalities, such as increased strong ion gap or decreased albumin, are associated with immunological activation; this association cannot be explained by illness severity alone.
Using a surveillance culture-based algorithm could reduce the use of broad-spectrum antibiotics and may be preferable when implementing new stewardship programs.
The adaptive immune system is suppressed early in the course of pediatric septic shock and is associated with adverse infection-related outcomes.
Plasma and urinary neutrophil gelatinase-associated lipocalin (pNGAL, uNGAL) levels measured upon admission to the ICU can be used to predict an occurrence of acute kidney injury (AKI) for up to 72 hours.
Yamamoto and Pop-Vicas review the major challenge of treating infections caused by Carbapenem-resistant Enterobacteriaceae, including what therapies have been successful and the antimicrobials currently in development.
Brad Spellberg reviews the rising problem of antibiotic resistance, discussing the reasons for the lack of new antibiotics and ways to encourage new development.
Volume 18 Suppl 1 (17 March 2014)
Brussels, Belgium. 18-21 March 2014
Aims & scope
Critical Care is a high quality, peer-reviewed, international clinical medical journal. Critical Care aims to improve the care of critically ill patients by acquiring, discussing, distributing, and promoting evidence-based information relevant to intensivists.
The journal publishes commentaries, reviews, and research in all areas of intensive care and emergency medicine. Critical Care aims to provide a comprehensive overview of the intensive care field.
Antibiotic resistance in the ICU
Edited by: Dr Steven Opal
Published: 27 June 2014
Selected articles from the Annual Update in Intensive Care and Emergency Medicine 2014
Published: 18 March 2014
All reviews, commentaries and reports published in Critical Care become free to access 12 months after publication. See below for the latest free review.
Alejandro Lazo-Langner, Eddy S Lang, James DouketisCritical Care 2013, 17:230
(17 June 2013)
- 10 July 2014
- Hospitals not using EHRs to upcode: study