Critical Care

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Acute kidney injury linked to increased risk for mortality among patients with pneumonia
[18 March 2010]

Complications common with nasal CPAP in neonatal intensive care unit
[17 March 2010]

Patient satisfaction influences mortality after AMI
[12 March 2010]

Benefit of PCI-center directed AMI care depends on referral region
[10 March 2010]

Prednisolone may not be helpful in community-acquired pneumonia
[9 March 2010]

Editor-in-Chief
Jean-Louis Vincent
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Affiliated to the International Symposium on Intensive Care and Emergency Medicine(ISICEM), Brussels, Belgium

Welcome to Critical Care

The online intensive care journal
Editor-in-Chief: Jean-Louis Vincent, Brussels, Belgium

Research highlight: ICU biomarker for increased hospital mortality

Intensive care unit blood lactate concentrations are independently associated with increased hospital mortality within currently defined 'normal' levels, allowing for easier diagnosis of critically ill patients at higher risk of death.

Critical Care 2010, 14:R25

Latest articles

	Research Enoxaparin - effective dosage for intensive care patients: double-blinded, randomised clinical trial Sian Robinson, Aleksander Zincuk, Thomas Strom, Torben Bjerregaard Larsen, Bjarne Rasmussen, Palle Toft Critical Care 2010, 14:R41 (18 March 2010) [Abstract] [Provisional PDF]

	Research Resuscitation with low volume hydroxyethylstarch 130kDa/0.4 is not associated with acute kidney injury Nicolas Boussekey, Raphael Darmon, Joachim Langlois, Serge Alfandari, Patrick Devos, Agnes Meybeck, Arnaud Chiche, Hugues Georges, Olivier Leroy Critical Care 2010, 14:R40 (18 March 2010) [Abstract] [Provisional PDF]

	Research Mechanical ventilation with high tidal volume induces inflammation in patients without lung disease Roselaine P Oliveira, Marcio P Hetzel, Mauro A Silva, Daniele Dallegrave, Gilberto Friedman Critical Care 2010, 14:R39 (18 March 2010) [Abstract] [Provisional PDF]

	Research Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial Pratik P Pandharipande, Robert D Sanders, Timothy D Girard, Stuart McGrane, Jennifer L Thompson, Ayumi K Shintani, Daniel L Herr, Mervyn Maze, E Wesley Ely, The MENDS Investigators Critical Care 2010, 14:R38 (16 March 2010) [Abstract] [Provisional PDF]

	Research Bedside adherence to clinical practice guidelines for enteral nutrition in critically ill patients receiving mechanical ventilation: a prospective, multi-centre, observational study Jean-Pierre Quenot, Gaetan Plantefeve, Jean-Luc Baudel, Isabelle Camilatto, Emmanuelle Bertholet, Romain Cailliod, Jean Reignier, Jean-Philippe Rigaud Critical Care 2010, 14:R37 (16 March 2010) [Abstract] [Provisional PDF]

	Research Alveolar fluid clearance in healthy pigs and influence of positive end-expiratory pressure Manuel Garcia-Delgado, Angel Touma-Fernandez, Virginia Chamorro-Marin, Antonio Ruiz-Aguilar, Eduardo Aguilar-Alonso, Enrique Fernandez-Mondejar Critical Care 2010, 14:R36 (16 March 2010) [Abstract] [Provisional PDF]

Thank you to all our reviewers in 2009

We are grateful for your help in ensuring Critical Care's authors receive prompt, thorough and constructive feedback on their work.

Open access

All research articles published in Critical Care are open access [more]

Image highlight

Effect of resin adsorption on septic plasma-induced alteration of adhesion to matrixes and TEC morphogenesis.

Latest supplements

Volume 14 Suppl 1
30th International Symposium on Intensive Care and Emergency Medicine
Abstracts

Volume 13 Suppl 5
Tissue oxygenation (StO₂) in healthy volunteers and critically-ill patients
Research

Volume 13 Suppl 4
Sepsis 2009
Abstracts

All articles published in supplements are fully peer reviewed.

Free review

All reviews, commentaries and reports published in Critical Care become free to access 12 months after publication. See below for the latest free review.

Review

Bench-to-bedside review: Oxygen as a drug

Haim Bitterman

Critical Care 2009, 13:205 (24 February 2009)

[Abstract][Full text][PDF] [PubMed] [Related articles]

Journal Club Critiques

From the University of Pittsburgh evidence-based medicine journal club

Journal club critique

Are specialized ICUs so special?

Yên-Lan C Nguyen, Eric B Milbrandt

Critical Care 2009, 13:314 (12 October 2009)

[Abstract] [Full Text] [PDF]

Latest comments

Oxygen consumption and lactic acidosis (Heikki Savolainen, 22Feb2010)
Dear Editor, The interesting investigation shows that the biguanidine treatment interferes with the oxygen consumption (1). This is compatible with the fact that eg. metformin... [read full comment]

Comment on: Protti A et al. Critical Care, 14:R22
Amino acid imbalance and encephalopathy (Heikki Savolainen, 12Feb2010)
Dear Editor, This investigations shows that infusion of LPS may alter the brain uptake of amino acids. It is thought that this may be a contributing factor to the clinical... [read full comment]

Comment on: Berg RMG et al. Critical Care, 14:R16
Vitamin D is also useful for septicemia (William B. Grant, 12Feb2010)
This is a great paper. Related to their finding is that vitamin D reduces the risk of septis/septicemia, in part through induction of cathelicidin and defensins, which have... [read full comment]

Comment on: Barbosa VM et al. Critical Care, 14:R5