- Jean-Louis Vincent, Erasme University Hospital
High numbers of false positive diagnoses of acute kidney injury could be occurring due to plasma neutrophil gelatinase-associated lipocalin (NGAL) increasing markedly with a reduction in glomerular filtration rate in stable chronic kidney disease patients.
In patients admitted with sepsis, plasma adrenomedullin could be used for mortality risk prediction as it is strongly associated with severity of disease, vasopressor requirement and 28-day mortality.
There is no superiority of leukodepleted over non-leukodepleted red blood cell (RBC) transfusions on microvascular perfusion in septic patients, but they appear to have a more favourable effect on microcirculatory convective flow.
Non-invasive ventilation with a synchronized and adaptable assist is equally, if not more, protective than low volume, invasive ventilation in rabbits with acute lung injury.
Heart rate variability (HRV) differs between patients with different weaning outcomes; measuring HRV change may help clinicians predict weaning results and improve patient care and outcomes.
Taccone and colleagues discuss practical approaches to post-anoxic brain injury when using therapeutic hypothermia after cardiac arrest, and how these tools can be used to improve outcome prediction.
Aims & scope
Critical Care is a high quality, peer-reviewed, international clinical medical journal. Critical Care aims to improve the care of critically ill patients by acquiring, discussing, distributing, and promoting evidence-based information relevant to intensivists.
The journal publishes commentaries, reviews, and research in all areas of intensive care and emergency medicine. Critical Care aims to provide a comprehensive overview of the intensive care field.
All reviews, commentaries and reports published in Critical Care become free to access 12 months after publication. See below for the latest free review.
Nino Stocchetti, Peter Roux, Paul Vespa, Mauro Oddo, Giuseppe Citerio, Peter J Andrews, Robert D Stevens, Tarek Sharshar, Fabio S Taccone, Jean-Louis VincentCritical Care 2013, 17:201
(15 January 2013)
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