EEG assessment of cerebral responsiveness during therapeutic neuromuscular blockade, and absence of potential artifacts from face muscle activity and eye blink. (a) Brief increase in higher frequencies normally associated with increased cognitive activity indicates cerebral response to a painful somatic stimuli. (b) Cerebral response to endotracheal suctioning in a therapeutically paralyzed patient. Dramatically increased high frequency waves, possibly indicating discomfort.
Crippen Critical Care 1997 1:15 doi:10.1186/cc3