|
|
||
| Clonidine |
Clomethiazole |
|
|
|
||
| Initial dose |
0.56 ± 0.22 mg |
0.78 ± 0.56 mg |
| Maintenance dose |
2.2 ± 1.5 mg/day |
5.2 ± 2.5 mg/day |
| Duration of treatment |
||
| ≤ 2 days |
14 (32.6%) |
7(14.6%) |
| 3-5 days |
22 (51.2%) |
22 (45.8%) |
| 6-10 days |
3 (7.0%) |
12 (25.0%) |
| Non-responder (≥ 10 days) |
4 (9.3%) |
7 (14.6%) |
| Enteral nutrition day 5 |
20 (46.5%) |
12 (25%) |
| Mobilisation |
||
| Regular respiration |
35 (81.4%) |
27 (56.3%) |
| Regular bowel function day 2 |
24 (55.8%) |
36 (75%) |
| Regular bowel function day 4 |
24 (55.8%) |
39 (81.3%) |
| Additive sedatives necessary |
36 (83.7%) |
24 (50%) |
Sehnert et al. Critical Care 1997 1(Suppl 1):P133 doi:10.1186/cc100 |
||