Figure 1.

Interaction of antithrombin with endothelium. The affinity of antithrombin (AT) to thrombin and its enzymatic inhibition is increased by binding of AT with the heparan-binding site to cellular heparin sulfate proteoglycans (HSPGs). TAT, thrombin–antithrombin.

Wiedermann Critical Care 2006 10:209   doi:10.1186/cc4822
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