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Cardiac troponin level is not an independent predictor of mortality in septic patients requiring medical intensive care unit admission

François G Brivet1*, Frédéric M Jacobs1, Patrice Colin2, Dominique Prat1 and Bogdan Grigoriu1

Author Affiliations

1 Medical Intensive Care Unit – Hôpital Antoine Béclère, Assistance Publique-Hôpitaux de Paris, France

2 Cardiologic Department – Hôpital Antoine Béclère, Assistance Publique-Hôpitaux de Paris, and Paris XI University, Paris, France

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Critical Care 2006, 10:404 doi:10.1186/cc3990

Published: 2 February 2006

First paragraph (this article has no abstract)

Turley and Gedney claim that the cardiac troponin Ic level is a predictor of adverse outcome [1] and that their results support those of King and colleagues [2]. Unfortunately, King and colleagues were unable to demonstrate a link between the troponin Ic level and mortality when using a multivariate model including the Acute Physiology Age and Chronic Health Evaluation II score. Interpretation of the results of Turley and Gedney therefore requires caution since their results are based only on univariate analysis [1].