Table 3 |
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Evolution of hemodynamic variables and catecholamine infusion rates after terlipressin therapy |
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|
Before terlipressin therapy |
Time after terlipressin therapy |
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|
|
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|
30 min |
60 min |
4 hours |
12 hours |
24 hours |
48 hours |
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|
|
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|
Systolic blood pressure (mmHg) |
77 (50–140) |
108 (61–154)* |
102.5 (61–137)* |
99 (65–147) |
91 (70–120) |
107 (55–118) |
105 (65–130) |
|
Mean blood pressure (mmHg) |
50.5 (37–93) |
77 (42–100)** |
69.5 (41–104)* |
74 (40–95) |
62 (40–90) |
68 (35–90) |
73 (40–103) |
|
Diastolic blood pressure (mmHg) |
38 (25–70) |
57 (32–72)* |
55.5 (31–90)* |
48 (25–86) |
50 (20–80) |
48 (26–77) |
53 (30–90) |
|
Heart rate (beats/min) |
155 (80–205) |
149 (114–186) |
148 (85–190) |
148 (110–190) |
146 (114–185) |
142 (102–170) |
148 (101–170) |
|
Central venous pressure (mmHg) |
14 (4–23) |
13 (3–23) |
12.5 (3–17) |
13 (3–27) |
12 (4–24) |
12 (5–18) |
13.6 (5–22) |
|
Catecholamines (µg/kg/min) |
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|
Noradrenaline |
2 (1–4) |
1 (0–3) |
1.15 (0–3) |
1.4 (0–2) |
1 (0–2.6)* |
1 (0–2.5)** |
0.1 (0–1)** |
|
Adrenaline |
1.2 (0.4–4) |
1 (0.5–6) |
1 (0.3–4) |
0.7 (0.2–3) |
0.6 (0.1–2) |
1 (0.2–2) |
0.5 (0–2.5) |
|
Dopamine |
21.5 (10–52) |
16.3 (3–40) |
17.5 (0–52) |
10 (0–40) |
15.8 (0–40) |
20 (3–40) |
11.6 (0–45) |
|
Dobutamine |
22.5 (5–40) |
20 (0–40) |
20 (0–40) |
20 (0–40) |
20 (0–40) |
20 (0–40) |
22.5 (10–30) |
|
Inotropic equivalenta |
176 (141–552) |
153.5 (67–460) |
128.5 (57–340) |
117.5 (20–340)* |
82 (0–371)** |
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|
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aInotropic equivalent: (noradrenaline × 100) + (adrenaline × 100) + dopamine + dobutamine + (milrinone × 15) [25]. * P < 0.05 versus baseline. ** P < 0.01 versus baseline. |
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|
Rodríguez-Núñez et al. Critical Care 2006 10:R20 doi:10.1186/cc3984 |
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