Table 2

Individual and mean pharmacokinetic parameters of ceftazidime
Pharmacokinetic parameters
 Css
 AUC0–72
 CLtot
 Vd
 T1/2
Patient 1
 35.2
 2625.0
 59.2
 19.0
 3.7
Patient 2
 34.3
 2655.0
 60.8
 12.4
 2.8
Patient 3
 28.8
 2146.0
 72.3
 17.7
 2.8
Patient 4
 32.5
 2372.0
 64.1
 29.4
 5.3
Patient 5
 36.3
 2795.0
 57.5
 24.1
 5.0
Patient 6
 33.6
 2471.0
 62.0
 13.7
 2.6
Patient 7
 34.2
 2536.0
 61.0
 15.8
 3.0
Mean
 33.5
 2514.3
 62.4
 18.9
 3.6
Standard deviation
 2.4
 211.8
 4.8
 6.0
 1.1

AUC0–72 h, area under the concentration time-curve from time zero to 72 hours (mg/hour per l); CLtot, total clearance of ceftazidime (ml/min); Css, steady-state serum ceftazidime concentration (mg/l); T1/2, elimination half-life (hours); Vd, volume of distribution (l).

Mariat et al. Critical Care 2006 10:R26   doi:10.1186/cc3993