Critical Care

official impact factor 4.60

Commentary

Rescue therapy in septic shock – is terlipressin the last frontier?

Marc Leone and Claude Martin*

Author Affiliations

Intensive Care Unit and Trauma Center, Nord University Hospital, Marseilles School of Medicine, Marseilles, France

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Critical Care 2006, 10:131 doi:10.1186/cc4863

Published: 21 March 2006

Abstract

Use of terlipressin, an analogue of vasopressin, can be considered in septic shock patients with intractable hypotension and high cardiac output in whom fluid resuscitation and high-dose conventional catecholamines have failed. The effects of this agent on organ function are poorly evaluated in humans. The limited number of patients evaluated precludes any analysis of adverse outcomes and prognosis.