Skin microcirculation and vasopressin infusion: a laser Doppler study

doi:10.1186/cc4884

Critical Care
Volume 10
Issue 2

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Commentary

Skin microcirculation and vasopressin infusion: a laser Doppler study

Francis Bernard¹, Alain Vinet²^,3 and Colin Verdant¹^,3

¹Intensive Care Service, Hôpital du Sacré-Coeur de Montréal, Université de Montréal, Montreal, Quebec, Canada

²Department of Physiology and Institute of Biomedical Engineering, Université de Montréal, Montreal, Quebec, Canada

³Hôpital du Sacré-Coeur de Montréal Research Center, Montreal, Quebec, Canada

author email corresponding author email

Critical Care 2006, 10:135doi:10.1186/cc4884


Published:	29 March 2006

See related research article http://ccforum.com/content/10/2/R40

Abstract

Use of arginine vasopressin in the management of refractory vasodilatory shock has been associated with development of ischaemic skin lesions. Because of the increasing popularity of arginine vasopressin, it is important to evaluate its effects on microcirculatory blood flow. Such studies are crucial if we are to appreciate the microcirculatory consequences of our various resuscitation strategies. However, methodological issues must always be considered because they can significantly influence interpretation of the results. Some aspects of use of laser Doppler to evaluate the microcirculation are reviewed within the context of recent findings presented by Luckner and coworkers in this issue of Critical Care.