Table 1

Changes in haemodynamic variables, acid-base status, reactive hyperaemia, and vasomotion
Parameters
 Group
 Baseline
 1 hour
 P
MAP (mmHg)
 AVP/NE*
 64 ± 5
 81 ± 12
 0.047†

NE
 64 ± 9
 66 ± 13
CI (l/min per m2)
 AVP/NE
 4.1 ± 1.2
 3.8 ± 1.1
 0.152

NE
 3.5 ± 0.9
 3.5 ± 0.8
DO2I (ml/min/m2)
 AVP/NE
 571 ± 140
 526 ± 130
 0.151

NE
 482 ± 111
 493 ± 119
VO2I (mL/min/m2)
 AVP/NE
 155 ± 39
 157 ± 35
 0.077

NE
 131 ± 35
 137 ± 41
SvO2 (%)
 AVP/NE
 72 ± 6
 66 ± 13
 0.583

NE
 71 ± 9
 70 ± 10
NE requirements (μg/kg per min)
 AVP/NE*
 0.75 ± 0.31
 0.51 ± 0.19
 0.36

NE
 0.65 ± 0.23
 0.76 ± 0.18
Milrinone requirements (μg/kg per min)
 AVP/NE
 0.44 ± 0.15
 0.44 ± 0.16
 0.025†

NE
 0.31 ± 0.2
 0.29 ± 0.19
pH
 AVP/NE
 7.30 ± 0.12
 7.30 ± 0.12
 0.355

NE
 7.33 ± 0.1
 7.32 ± 0.08
Lactate (mmol/l)
 AVP/NE
 5.9 ± 6.7
 6.6 ± 6.3
 0.548

NE
 7.6 ± 6.1
 7.5 ± 5.6
AUC pre-ischaemic
 AVP/NE
 21.2 ± 9.4
 16.7 ± 7.7
 0.089

NE
 15.3 ± 10.2
 15.3 ± 9.0
Magnitude of RH (%)
 AVP/NE
 64 ± 57.2
 70 ± 47.5
 0.56

NE
 49.4 ± 24.8
 48.7 ± 41.7
ODS pre-ischaemic (oscillations/min)
 AVP/NE‡
 15.73 ± 5.15
 14.38 ± 7.31
 0.055§

NE
 7.49 ± 3.2
 10.7 ± 3.81
ODS reperfusion (oscillations/min)
 AVP/NE‡
 14.38 ± 4.85
 13.78 ± 9.17
 0.601§

NE
 8.99 ± 3.92
 10.7 ± 5.7

Data are expressed as mean values ± standard deviation. AUC, area under the curve; AVP, arginine vasopressin; CI, cardiac index; DO2I, systemic oxygen transport index; MAP, mean arterial pressure; NE, norepinephrine; ODS, oscillation of the Doppler signal; RH, reactive hyperaemia; SvO2, mixed venous oxygen saturation; VO2I, systemic oxygen consumption index. *significant difference over time; †, significant difference between groups; ‡, significant difference at baseline between groups; §, corrected for baseline differences.

Luckner et al. Critical Care 2006 10:R40   doi:10.1186/cc4845