Table 2 |
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|
Correlation of time-related cytokine production with organ dysfunctions measured within 24 hours after surgery |
|||||
|
Organ dysfunction |
Inflammatory markers |
p |
|||
|
|
|||||
|
AI |
After CPB |
||||
|
|
|||||
|
3 hours |
6 hours |
10 hours |
|||
|
|
|||||
|
Circulationa |
MIF |
0.017 |
|||
|
IL-10 |
0.011 |
||||
|
IL-6 |
0.05 |
||||
|
Hematologicalb |
MCP-1 |
0.014 |
|||
|
MCP-1 |
0.026 |
||||
|
MCP-1 |
0.002 |
||||
|
Pulmonaryc |
MIF |
0.041 |
|||
|
MIF |
<0.001 |
||||
|
IL-10 |
0.032 |
||||
|
|
|||||
|
aDefined as noreprinephrine > 1.0 μg/kg per minute; bdefined as platelets < 133,000/mm3; cdefined as a ratio of partial arterial oxygen tension to fraction of inspired oxygen of less than 196. AI, anesthesia induction; CPB, cardiopulmonary bypass; MCP, monocyte chemoattractant protein; MIF, macrophage migration inhibitory factor. |
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|
de Mendonça-Filho et al. Critical Care 2006 10:R46 doi:10.1186/cc4857 |
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