|
Sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio of inflammatory markers in diagnosing sepsis |
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| Variable |
Cut-off level |
Sensitivity (%) |
Specificity (%) |
Positive predictive value (%) |
Negative predictive value (%) |
Positive likelihood ratio |
Negative likelihood ratio |
|
|
|||||||
| Procalcitonin |
0.087 ng/ml |
79.7 |
42.1 |
84.3 |
34.8 |
1.4 |
0.48 |
| 0.1 ng/ml |
75.7 |
52.6 |
86.2 |
35.7 |
1.6 |
0.46 |
|
| 0.25 ng/ml |
55.0 |
89.5 |
95.4 |
34.0 |
5.2 |
0.5 |
|
| 0.5 ng/ml |
45.9 |
89.5 |
94.4 |
29.8 |
4.4 |
0.6 |
|
| Lipopolysaccharide-binding protein |
20 μg/ml |
81.0 |
68.4 |
90.9 |
48.2 |
2.6 |
0.28 |
| 40 μg/ml |
41.9 |
100.0 |
100.0 |
30.7 |
0.58 |
||
| C-reactive protein |
38 mg/l |
79.7 |
57.9 |
88.1 |
42.3 |
1.9 |
0.35 |
| 50 mg/l |
71.6 |
63.2 |
88.3 |
36.4 |
1.9 |
0.45 |
|
| 100 mg/l |
63.5 |
94.7 |
97.9 |
40.0 |
11.9 |
0.39 |
|
| IL-6 |
25 pg/ml |
81.1 |
78.9 |
93.8 |
51.7 |
3.8 |
0.24 |
| 50 pg/ml |
70.3 |
89.5 |
96.3 |
43.6 |
6.7 |
0.33 |
|
Gaïni et al. Critical Care 2006 10:R53 doi:10.1186/cc4866 |
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