Critical Care

official impact factor 4.60

Highly Access

Drotrecogin alfa (activated): does current evidence support treatment for any patients with severe sepsis?

Jan O Friedrich*, Neill KJ Adhikari and Maureen O Meade

Critical Care 2006, 10:145 doi:10.1186/cc4947

Accesses  

  • Last 30 days: 36 accesses
  • Last year: 476 accesses
  • All time: 5815 accesses

Cited by

BioMed Central: 7 citations

Commentary   Free

Effect of sepsis therapies on health-related quality of life

Sara E Erickson, Greg S Martin Critical Care 2008, 12:109 (22 January 2008)

Research article   Open Access Highly Accessed

Drotrecogin alfa (activated) in severe sepsis: a systematic review and new cost-effectiveness analysis

Vania Costa, James M Brophy BMC Anesthesiology 2007, 7:5 (25 June 2007)

A systematic review and economic analysis of the use of drotecogin alpha questions its clinical efficacy and cost effectiveness in the treatment of adults with sepsis, including those with higher disease severity.

Letter   Free

Drotrecogin alfa (activated) in patients with severe sepsis and a high risk of death

Jan O Friedrich, Neill KJ Adhikari, Maureen O Meade Critical Care 2006, 10:427 (20 December 2006)

Letter   Free Highly Accessed

Drotrecogin alfa (activated): current evidence supports treatment for severe sepsis patients with a high risk of death

Mark D Williams, Jonathan M Janes, David R Nelson Critical Care 2006, 10:424 (30 October 2006)

Letter   Free

Drotrecogin alfa (activated): down and not out, but not really in either

Jan O Friedrich, Neill KJ Adhikari, Maureen O Meade Critical Care 2006, 10:420 (22 September 2006)

Letter   Free

Patience and change: a conflict of interests?

Manoj K Saxena, Peter JD Andrews Critical Care 2006, 10:422 (19 September 2006)

Letter   Free Highly Accessed

Activated protein C in sepsis: down but not out, yet

Ritesh Agarwal, Alok Nath Critical Care 2006, 10:416 (26 July 2006)