Table 5 |
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|
Association of Risk, Injury, Failure, Loss, and End-stage Kidney (RIFLE) criteria with mortality |
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|
Hazard ratio (95% confidence interval) |
P |
|
|
|
||
|
Panel A: association of AKI, defined by meeting any RIFLE criteria, with mortality |
||
|
AKI (reference no AKI) |
1.7 (1.28–2.13) |
< 0.001 |
|
SOFAnonrenal score (per point) |
1.1 (1.10–1.15) |
< 0.001 |
|
Age (per 10 years) |
1.1 (1.07–1.18) |
< 0.001 |
|
Sex (female) |
0.9 (0.78–1.07) |
0.252 |
|
Race (reference white) |
0.528 |
|
|
Black |
1.1 (0.88–1.45) |
0.324 |
|
Other |
0.8 (0.41–1.68) |
0.608 |
|
Medical admission (reference surgical admission) |
2.9 (2.44–3.40) |
< 0.001 |
|
Main reason for admission (reference cardiovascular disease) |
< 0.001 |
|
|
Trauma |
0.9 (0.66–1.09) |
0.196 |
|
Neurological disease |
1.3 (1.03–1.52) |
0.026 |
|
Pulmonary disease, infection |
0.8 (0.65–1.03) |
0.087 |
|
Gastrointestinal disease |
0.5 (0.21–1.25) |
0.140 |
|
Malignancy |
0.2 (0.04–0.63) |
0.009 |
|
Other |
0.4 (0.22–0.62) |
< 0.001 |
|
Panel B: association of maximum RIFLE class with mortality |
||
|
RIFLEmax (reference no AKI) |
< 0.001 |
|
|
Risk |
1.0 (0.68–1.56) |
0.896 |
|
Injury |
1.4 (1.02–1.88) |
0.037 |
|
Failure |
2.7 (2.03–3.55) |
< 0.001 |
|
SOFAnonrenal score (per point) |
1.1 (1.10–1.14) |
< 0.001 |
|
Age (per 10 years) |
1.1 (1.08–1.20) |
< 0.001 |
|
Sex (female) |
0.9 (0.76–1.06) |
0.190 |
|
Race (reference white) |
0.673 |
|
|
Black |
1.1 (0.87–1.45) |
0.389 |
|
Other |
0.9 (0.44–1.97) |
0.844 |
|
Medical admission (reference surgical admission) |
2.7 (2.27–3.21) |
< 0.001 |
|
Main reason for admission (reference cardiovascular disease) |
< 0.001 |
|
|
Trauma |
0.9 (0.69–1.18) |
0.463 |
|
Neurological disease |
1.3 (1.06–1.60) |
0.011 |
|
Pulmonary disease, infection |
0.8 (0.66–1.07) |
0.154 |
|
Gastrointestinal disease |
0.6 (0.24–1.41) |
0.230 |
|
Malignancy |
0.2 (0.04–0.69) |
0.013 |
|
Other |
0.3 (0.20–0.60 |
< 0.001 |
|
|
||
|
Covariate-adjusted Cox proportional hazard regression analysis. AKI, acute kidney injury, patients meeting at least one of the RIFLE criteria; RIFLEmax, maximum RIFLE class; SOFAnonrenal, Sequential Organ Failure Assessment score without points for kidney failure, determined on data from the first 24 hours of admission. |
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|
Hoste et al. Critical Care 2006 10:R73 doi:10.1186/cc4915 |
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