Table 2

Arteriolar diameter, cross-sectional area, blood velocity, and arteriolar flow in norepinephrine and arginine vasopressin animals

Arteriol type

Parameter

Drug

Baseline

Drug infusion

Change (%)

p value

A0

Arteriolar D (μm)

NE^a

127 ± 27

86 ± 16

31 ± 12

0.002^b

AVP^a

129 ± 7

66 ± 12

49 ± 7

Arteriolar CSA (μm²)

NE^a

13,083 ± 4,908

5,954 ± 2,150

49 ± 17

0.002^b

AVP^a

13,100 ± 1,462

3,547 ± 1,173

73 ± 7

RBC velocity (mm/s)

NE^a

13.5 ± 2.2

10.6 ± 2.3

22 ± 9

0.232

AVP^a

14.9 ± 0.9

11.2 ± 1.1

25 ± 6

Arteriolar BF (10^-2 × mm × μm²/s)

NE^a

18.4 ± 8.1

6.6 ± 3.2

62 ± 13

0.004^b

AVP^a

19.6 ± 2.6

3.9 ± 1.3

80 ± 6

A1

Arteriolar D (μm)

NE^a

47 ± 11

33 ± 8

28 ± 12

0.461

AVP^a

49 ± 13

66 ± 12

30 ± 12

Arteriolar CSA (μm²)

NE^a

1,785 ± 878

922 ± 444

47 ± 16

0.461

AVP^a

2,000 ± 1,080

987 ± 574

50 ± 17

RBC velocity (mm/s)

NE^a

3.7 ± 0.7

3 ± 0.4

19 ± 9

0.236

AVP^a

3.9 ± 1

2.9 ± 1.2

27 ± 17

Arteriolar BF (10^-3 × mm × μm²/s)

NE^a

6.9 ± 4.1

2.8 ± 1.5

57 ± 15

0.096

AVP^a

8.2 ± 6.2

2.9 ± 2.4

63 ± 14

A2

Arteriolar D (μm)

NE^a

28 ± 12

20 ± 9

29 ± 12

0.156

AVP^a

25 ± 8

16 ± 5

34 ± 14

Arteriolar CSA (μm²)

NE^a

748 ± 689

390 ± 332

48 ± 16

0.156

AVP^a

522 ± 345

226 ± 141

55 ± 18

RBC velocity (mm/s)

NE^a

3 ± 0.7

2.3 ± 0.4

20 ± 14

0.845

AVP^a

2.8 ± 0.4

2.2 ± 0.4

21 ± 15

Arteriolar BF (10^-3 × mm × μm²/s)

NE^a

2.6 ± 3.3

0.9 ± 1.0

59 ± 13

0.212

AVP^a

1.5 ± 1.2

0.5 ± 0.4

64 ± 19

A3

Arteriolar D (μm)

NE^a

15 ± 6

10 ± 5

34 ± 11

0.110

AVP^a

16 ± 5

9 ± 3

43 ± 12

Arteriolar CSA (μm²)

NE^a

193 ± 180

86 ± 96

56 ± 14

0.110

AVP^a

86 ± 96

74 ± 51

86 ± 13

RBC velocity (mm/s)

NE^a

2.3 ± 0.4

1.8 ± 0.4

21 ± 16

0.146

AVP^a

2.4 ± 0.4

1.7 ± 0.6

29 ± 16

Arteriolar BF (10^-4 × mm × μm²/s)

NE^a

4.7 ± 4.9

1.6 ± 1.6

65 ± 12

0.013

AVP^a

5.6 ± 4.9

1.3 ± 1.3

76 ± 11

A4

Arteriolar D (μm)

NE^a

9 ± 3

6 ± 1

32 ± 8

0.206

AVP^a

9 ± 2

7 ± 2

26 ± 12

Arteriolar CSA (μm²)

NE^a

70 ± 62

28 ± 14

53 ± 10

0.206

AVP^a

74 ± 41

39 ± 20

44 ± 18

RBC velocity (mm/s)

NE^a

1.7 ± 0.3

1.3 ± 0.3

21 ± 14

0.464

AVP^a

1.5 ± 0.3

1.1 ± 0.1

27 ± 19

Arteriolar BF (10^-4 × mm × μm²/s)

NE^a

1.3 ± 1.4

0.4 ± 0.3

63 ± 10

0.837

AVP^a

1.2 ± 0.9

0.5 ± 0.3

57 ± 21

Data are given as mean values ± standard deviation. ^aSignificant difference between baseline and drug infusion. ^bSignificant difference of change (%) between arginine vasopressin (AVP) and norepinephrine (NE) animals. BF, blood flow; CSA, cross-sectional area; D, diameter; RBC, red blood cell.

Friesenecker et al. Critical Care 2006 10:R75   doi:10.1186/cc4922