Table 2

Concentrations of tumour necrosis factor-alpha (TNFα), interleukin(IL)-6 and IL-8 in relation to monocyte apoptosis (≤50% or >50%) of the first day

Day

Sepsis

Severe sepsis

Septic shock

≤50% (n = 20)

>50% (n = 7)

≤50% (n = 18)

>50% (n = 9)

≤50% (n = 19)

>50% (n = 17)

Tumour necrosis factor alpha

1

4.97 ± 1.91

4.95 ± 0.20

6.84 ± 0.97

7.33 ± 28.20

6.98 ± 11.21

6.85 ± 3.29

3

7.28 ± 4.39

5.23 ± 19.50

5.70 ± 37.30

5.16 ± 1.48

5.15 ± 14.45

9.98 ± 1.74

5

5.33 ± 0.86

5.08 ± 5.03

6.37 ± 10.92

7.39 ± 2.26

10.32 ± 30.03

9.36 ± 7.52

7

6.22 ± 4.37

6.58 ± 0.63

4.83 ± 3.23

5.92 ± 2.22

12.44 ± 18.41

6.12 ± 3.20*

IL-6

1

95.4 ± 24.2

123.1 ± 61.1

102.9 ± 20.3

69.4 ± 26.4

212.3 ± 30.7

88.3 ± 25.3*

3

80.1 ± 21.2

63.7 ± 27.7

96.6 ± 26.1

114.6 ± 31.8

141.2 ± 25.7

83.2 ± 22.1

5

89.4 ± 25.4

112.2 ± 50.1

96.5 ± 23.1

98.7 ± 38.3

128.2 ± 36.0

76.5 ± 23.4

7

61.3 ± 21.3

41.4 ± 49.5

107.2 ± 24.7

99.9 ± 27.9

160.4 ± 30.2

57.4 ± 23.6*

IL-8

1

181.5 ± 152.9

403.6 ± 315.1

62.5 ± 33.3

62.5 ± 143.2

255.4 ± 126.5

62.5 ± 72.7*

3

152.4 ± 145.2

62.5 ± 91.2

62.5 ± 31.8

62.5 ± 230.9

95.3 ± 140.8

62.5 ± 119.7

5

62.5 ± 54.7

423.5 ± 103.2

62.5 ± 70.0

314.6 ± 210.2

623.8 ± 206.6

62.5 ± 123.5*

7

99.9 ± 114.4

62.5 ± 80.9

62.5 ± 88.9

108.1 ± 281.6

128.1 ± 281.6

355.2 ± 94.4

Data presented as the median ± standard error (pg/ml). *P < 0.05 compared with patients of the same group with apoptosis ≤50%.

Giamarellos-Bourboulis et al. Critical Care 2006 10:R76   doi:10.1186/cc4921