Table 1

Hemodynamic data at baseline and during conventional ventilation and open lung ventilation


Baseline
Conventional mechanical ventilation
Open lung ventilation

Heart rate (beats/min)
105 ± 5
86 ± 5**
94 ± 5
Mean arterial pressure (mmHg)
93 ± 4
104 ± 4**
80 ± 4*,**
Right atrial pressure (mmHg)
4.2 ± 1
5.9 ± 1**
8.1 ± 2**
Cardiac output (l/min)
5.3 ± 0.3
4.9 ± 0.3
4.1 ± 0.3*,**
Right ventricular end-diastolic volume (ml)
165 ± 11
173 ± 13
148 ± 13
Right ventricular end-systolic volume (ml)
112 ± 10
119 ± 11
103 ± 11
Systolic pulmonary pressure (mmHg)
30 ± 3
31 ± 3
28 ± 2
Mean pulmonary arterial pressure (mmHg)
17 ± 3
20 ± 2
17 ± 2*
Pulmonary capillary wedge pressure (mmHg)
9.3 ± 2
12.1 ± 3
12.5 ± 2**
Right ventricular ejection fraction (%)
33.1 ± 1.7
33.1 ± 1.7
31.1 ± 1.9
Pulmonary vascular resistance (dynes/s/cm5)
126 ± 38
130 ± 34
137 ± 49
Left ventricular end-diastolic volume (ml)
66 ± 4
61 ± 3
56 ± 5**
Systemic vascular resistance (dynes sec cm5)
1379 ± 120
1693 ± 139**
1508 ± 124
Left ventricular ejection fraction (ml)
49.5 ± 1.6
53.2 ± 2.1
43.2 ± 5.6

*P < 0.05 open lung ventilation versus conventional mechanical ventilation, **P < 0.05 versus baseline.

Reis Miranda et al. Critical Care 2006 10:R86   doi:10.1186/cc4944