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Hemodynamic data at baseline and during conventional ventilation and open lung ventilation |
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| Baseline |
Conventional mechanical ventilation |
Open lung ventilation |
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| Heart rate (beats/min) |
105 ± 5 |
86 ± 5** |
94 ± 5 |
| Mean arterial pressure (mmHg) |
93 ± 4 |
104 ± 4** |
80 ± 4*,** |
| Right atrial pressure (mmHg) |
4.2 ± 1 |
5.9 ± 1** |
8.1 ± 2** |
| Cardiac output (l/min) |
5.3 ± 0.3 |
4.9 ± 0.3 |
4.1 ± 0.3*,** |
| Right ventricular end-diastolic volume (ml) |
165 ± 11 |
173 ± 13 |
148 ± 13 |
| Right ventricular end-systolic volume (ml) |
112 ± 10 |
119 ± 11 |
103 ± 11 |
| Systolic pulmonary pressure (mmHg) |
30 ± 3 |
31 ± 3 |
28 ± 2 |
| Mean pulmonary arterial pressure (mmHg) |
17 ± 3 |
20 ± 2 |
17 ± 2* |
| Pulmonary capillary wedge pressure (mmHg) |
9.3 ± 2 |
12.1 ± 3 |
12.5 ± 2** |
| Right ventricular ejection fraction (%) |
33.1 ± 1.7 |
33.1 ± 1.7 |
31.1 ± 1.9 |
| Pulmonary vascular resistance (dynes/s/cm5) |
126 ± 38 |
130 ± 34 |
137 ± 49 |
| Left ventricular end-diastolic volume (ml) |
66 ± 4 |
61 ± 3 |
56 ± 5** |
| Systemic vascular resistance (dynes sec cm5) |
1379 ± 120 |
1693 ± 139** |
1508 ± 124 |
| Left ventricular ejection fraction (ml) |
49.5 ± 1.6 |
53.2 ± 2.1 |
43.2 ± 5.6 |
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*P < 0.05 open lung ventilation versus conventional mechanical ventilation, **P < 0.05 versus baseline. | |||
Reis Miranda et al. Critical Care 2006 10:R86 doi:10.1186/cc4944 |
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