Table 1

Volumetric variables in sheep breathing spontaneously, or subjected to mechanical ventilation, or pneumonectomy

Parameter
SB (n = 48)
MV (n = 51)
PE (n = 42)

ITBVI (ml/m2)
856 ± 106
804 ± 129
635 ± 116b,c
GEDVI (ml/m2)
654 ± 92
551 ± 91b
461 ± 97b,c
PBVI (ml/m2)
202 ± 32
253 ± 56b
176 ± 41b,c
ITBV:GEDV ratio
1.313 ± 0.063
1.463 ± 0.089b
1.389 ± 0.101b,c
Correlation between ITBVI and GEDVa
0.96
0.93
0.95
Regression equation
ITBVI = 1.16 × GEDVI + 92.45
ITBVI = 1.43 × GEDVI + 13.48
ITBVI = 1.21 × GEDVI + 73.72

SB, spontaneous breathing; MV, mechanical ventilation with tidal volumes of 6 to 8 ml/kg and positive end-expiratory pressure 2 cmH2O; PE, pneumonectomy; ITBVI, intrathoracic blood volume index; GEDVI, global end-diastolic volume index; PBVI, pulmonary blood volume index; ITBV, intrathoracic blood volume; GEDV, global end-diastolic volume. All data are distributed normally and are presented as means ± SD. aPearson coefficient, r (p < 0.0001). bp < 0.05 compared with SB; cp < 0.05 compared with MV (analysis of variance followed by Scheffe's test).

Kirov et al. Critical Care 2006 10:415   doi:10.1186/cc4989