Table 2 |
||
|
Demographic data and genotype frequencies of TNF and IL-10 polymorphisms in patients with sepsis and controls. |
||
|
Patients (n = 224) |
Control individuals (n = 101) |
|
|
|
||
|
Age |
63.5 (49–72.75) |
50 (46.5–55.5) |
|
APACHE II |
14 (9–19) |
- |
|
SOFA (1)a |
4 (2–9) |
- |
|
-308 TNF-α promoter polymorphism |
||
|
GG |
186 (83) |
82 (81.2) |
|
GA |
35 (15.6) |
15 (14.9) |
|
AA |
3 (1.4) |
4 (3.9) |
|
TNF-β (NcoI polymorphism) |
||
|
GG |
16 (7.1) |
10 (9.9) |
|
GA |
69 (30.8) |
34 (33.7) |
|
AA |
139 (62.5) |
57 (56.4) |
|
IL-10-1082 |
||
|
GG |
33 (14.8) |
15 (14.8) |
|
GA |
99 (44.2) |
50 (49.5) |
|
AA |
92 (41) |
36 (35.7) |
|
|
||
|
Values are expressed as median (25th to 75th percentile) or as n (%).aSOFA (1) means SOFA score of the first 24 hours in the hospital. APACHE, Acute Physiology and Chronic Health Evaluation score; SOFA, Sequential Organ Failure Assessment; TNF, tumour necrosis factor. |
||
|
Garnacho-Montero et al. Critical Care 2006 10:R111 doi:10.1186/cc4995 |
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