Serum uric acid, creatinine, and the assessment of antioxidant capacity in critical illness

doi:10.1186/cc5008

Critical Care

Volume 10
Issue 5

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Giovannini I
Chiarla C
Giuliante F
Pallavicini F
Vellone M
Ardito F
Nuzzo G

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Giovannini I
Chiarla C
Giuliante F
Pallavicini F
Vellone M
Ardito F
Nuzzo G
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Letter

Serum uric acid, creatinine, and the assessment of antioxidant capacity in critical illness

Ivo Giovannini , Carlo Chiarla, Felice Giuliante, Federico Pallavicini, Maria Vellone, Francesco Ardito and Gennaro Nuzzo

Hepato-biliary Surgery Unit, Sub-intensive Care, and CNR-IASI Center for the Pathophysiology of Shock, Catholic University School of Medicine, Rome, Italy

author email corresponding author email

Critical Care 2006, 10:421doi:10.1186/cc5008


Published:	4 September 2006

See related research article by Chuang et al., http://ccforum.com/content/10/1/R36

First paragraph (this article has no abstract)

In their nice study on serum total antioxidant capacity (TAC) in sepsis [1] Chuang and coworkers have demonstrated an increase in TAC that was directly correlated to severity of illness and poor outcome, and to increasing levels of serum uric acid (UA). Although the increase in TAC might be interpreted as an extreme protective attempt against overwhelming inflammation, this must still be proved, as correctly commented on by the authors.