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Letter

Patience and change: a conflict of interests?

Manoj K Saxena* and Peter JD Andrews

Author Affiliations

Department of Intensive Care, University of New South Wales, St George Hospital, Gray Street, Kogarah, NSW 2217, Australia

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Critical Care 2006, 10:422 doi:10.1186/cc5034

Published: 19 September 2006

First paragraph (this article has no abstract)

While we must applaud industry and the Recombinant Human Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) investigators [1] for the tremendous effort and time expended in their multicentre, international study, caution needs to be exercised before deciding to make the intervention of activated protein C (APC) a standard of treatment [2].