Table 1

Hemodynamic data, blood gas data in pressure-controlled ventilation (PCV) pre-lavage, PCV post-lavage, and during lung volume optimization procedure in high-frequency oscillatory ventilation


PCV pre-lavage
PCV post-lavage
45 mbar

Heart rate (beats/minute)
113 (112–124)
112 (102–125)
141 (126–167)
Right atrial pressure (mmHg)
9 (9–9)
10 (8–11)
16 (15–18)**
Mean pulmonary artery pressure (mmHg)
25 (20–37)
34 (30–41)
41 (35.7–52)**
Pulmonary occlusion pressure (mmHg)
10 (7–12)
13 (11–13)
24 (23–26)**
Left ventricular end-diastolic pressure (mmHg)
3 (1–4)
3.5 (2–6)
12 (11–13)**
Mean arterial pressure (mmHg)
89.5 (67–106)
83 (82–85)
85 (66–89)
Cardiac output (l/min)
3.28 (3.1–3.5)
3.6 (3.1–3.9)
2.6 (2.3–3.1)**
Stroke volume (ml)
31 (27–36)
32 (31–35)
19 (18–24)**
Intrathoracic blood volume (ml)
598.5 (548–622)
594 (553–690)
442 (401–469)
Extravascular lung water (ml)
290 (241–311)
420 (354–463)*
355 (315–476)
Systemic vascular resistance (dyn*s/cm5)
1817 (1277–2508)
1542 (1450–2074)
2403 (1524–2585)
Pulmonary vascular resistance (dyn*s/cm5)
266 (213–775)
545 (275–693)
639 (404–859)
Mean pulmonary artery pressure–right atrial pressure (mmHg)
16 (11–28)
26 (22–30)
28 (19–34)
Transpulmonary pressure (mbar)
4.5 (4–6)
10 (8–11)*
36 (32–43)**
PaO2 (Torr)
559 (535–658)
99 (56–128)*
621 (557–522)**
PaO2/FiO2 ratio
559 (535–658)
99 (56–128)*
621 (557–522)**
Oxygenation index
1.4 (1.2–2)
16.3 (14.6–21.3)*
7.2 (6.8–7.2)**
Oxygen delivery (ml O2/minute)
408.3 (382.5–427.6)
373 (297.6–427.9)
312 (299–466.2)
Shunt proportion
9.9 (8.8–11)
51.8 (49–55)*
1.03 (0.4–3)**
PaCO2 (Torr)
39.6 (32.8–48.4)
47 (40.7–58.8)
38.5 (28.3–46.6)
Oxygen saturation (%)
99.9 (99.9–99.9)
92 (89.7–96.5)*
99.9 (99–100)**
pH
7.45 (7.4–7.5)
7.38 (7.31–7.4)
7.41 (7.37–7.5)
Standard bicarbonate (mmol/l)
28.2 (27.8–30.2)
28.5 (26.2–30.9)
25 (23.2–27.5)
Base excess
4.8 (2.1–5.9)
2.25 (1–2.9)*
0.7 (-0.12 to 4.95)
Hemoglobin (g/dl)
7.6 (7.5–8)
7.8 (7.4–8.3)
7.9 (7.1–9.7)
Plateau airway pressure (cmH20)
21 (10.8–14.4)
30 (25–35)

Inspiratory tidal volume (ml)
335 (330–450)
390 (310–440)

Dynamic lung compliance (ml/mbar)
12.6 (10.8–14.4)
7.9 (5.3–9.8)*


Data presented as median (25th–75th percentiles). *P < 0.05 vs PCV pre-lavage (Wilcoxon signed-rank test), **P < 0.05 vs PCV post-lavage.

Karmrodt et al. Critical Care 2006 10:R138   doi:10.1186/cc5052