|
Clinical, biological and infection data of patients |
|
| Sex |
|
| Female |
59 (57.8) |
| Male |
43 (42.2) |
| Age (years) |
74 (62–82) |
| Admission diagnoses |
|
| Postoperative |
47 (46.1) |
| Medical |
50 (49) |
| Trauma |
5 (4.9) |
| Acute respiratory distress syndrome |
52 (51) |
| Length of intensive care unit stay (days) |
18 (12–27.3) |
| Length of hospital stay (days) |
33 (19–85.3) |
| Days for corticotropin testa |
2 (1–4) |
| Total serum protein (g/dl)b |
4.7 (4.1–5.2) |
| Serum albumin (g/dl)b |
2 (1.7–2.4) |
| White blood cells (cells/μl) |
11,550 (8,275–16,500) |
| C-reactive protein (mg/dl) |
16.3 (10.5–25) |
| Baseline cortisol levels (μg/dl) |
17.2 (10.6–23.8) |
| Cortisol 60 (μg/dl) |
25.4 (18.6–39.2) |
| Cortisol 120 (μg/dl) |
35.5 (24.5–49.9) |
| Δmax1 (μg/dl) |
8.2 (3.5–17.3) |
| Δmax249 (μg/dl) |
16.6 (10–26) |
| Mean daily dose of norepinephrinec (μg/kg/minute) |
0.13 (0.04–0.54) |
| Sequential Organ Failure Assessment score (corticotropin test day) |
9 (7.8–11) |
| Maximum Sequential Organ Failure Assessment score |
10 (9–13) |
| First-day Sequential Organ Failure Assessment score |
7 (4–10) |
| Acute Physiologic and Chronic Heath Evaluation II score |
20 (17–23) |
| Simplified Acute Physiology II score |
43.5 (36–52.3) |
| 28-day mortality rate |
32 (31.4) |
| Intensive care unit mortality rate |
36 (35.3) |
| Hospital mortality rate |
46 (45.1) |
| Site of infection |
|
| ◦Intra-abdominal |
28 (27.5) |
| ◦Soft tissue abscess/cellulitis |
3 (2.9) |
| ◦Lung |
58 (56.9) |
| ◦Central nervous system |
1 (1) |
| ◦Urinary tract |
10 (9.8) |
| ◦Endovascular infection |
2 (2) |
| Microorganismsd |
|
| ◦Gram-negative bacillus |
72 (61.6) |
| ◦Gram-positive coccus |
39 (33.3) |
| ◦Fungus |
6 (5.1) |
| Bacteremia |
22 (21.6) |
| Type of infection |
|
| ◦Community |
51 (50) |
| ◦Nosocomial |
51 (50) |
|
Data presented as n (%) or median (interquartile range). Cortisol units: 1 μg/dl = 27.6 nmol/l. Cortisol 60, serum cortisol level drawn 60 minutes after stimulus with 1 μg corticotropin; Cortisol 120, serum cortisol level drawn 60 minutes after stimulus with 249 μg corticotropin (120 minutes after serum baseline cortisol); Δmax1, cortisol 60 value minus the baseline cortisol level; Δmax249, cortisol 120 value minus the baseline cortisol level. aDifference between corticotropin test day and intensive care unit admission day. bProtein and albumin levels were not measured in 15 patients. cMean daily dose of norepinephrine during the first five days after hydrocortisone usage or after the corticotropin test. dMicrobiological identification was obtained in 69 patients (67.6%). | |
Salgado et al. Critical Care 2006 10:R149 doi:10.1186/cc5077 |
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