|
Adrenal function according to the serum albumin level |
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| Albumin ≤ 2.5 g/dl (n = 75) |
Albumin > 2.5 g/dl (n = 12) |
P value |
|
|
|
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| Baseline cortisol (μg/dl) |
15.5 (10.4–23.4) |
22.4 (15.5–26.7) |
0.04* |
| Cortisol 60 (μg/dl) |
23.5 (17.2–36.6) |
40.3 (27–51.5) |
0.009* |
| Cortisol 120 (μg/dl) |
30.4 (23.2–46.7) |
41.9 (33.1–54.9) |
0.04* |
| Δmax1 (μg/dl) |
6.9 (3.5–13.2) |
13.2 (3.7–26.6) |
0.24 |
| Δmax249 (μg/dl) |
14.5 (9.4–23.4) |
18.8 (9.9–28.9) |
0.48 |
| Baseline cortisol ≤ 10 |
17 (22.7) |
1 (8.3) |
0.45 |
| Baseline cortisol ≤ 15 |
37 (49.3) |
3 (25) |
0.12 |
| Baseline cortisol ≤ 20 |
52 (69.3) |
6 (50) |
0.2 |
| Baseline cortisol ≤ 23.6 |
58 (77.3) |
6 (50) |
0.07 |
| Baseline cortisol ≤ 25 |
63 (84) |
7 (58.3) |
0.05* |
| Baseline cortisol ≤ 34 |
70 (93.3) |
11 (91.7) |
1.0 |
| Δmax249 ≤ 9 |
18 (24) |
3 (25) |
1.0 |
| Δmax1 ≤ 9 |
46 (61.3) |
4 (33.3) |
0.07 |
|
Data presented as n (%) or median (interquartile range). Protein and albumin levels were not measured in 15 patients. Cortisol units: 1 μg/dl = 27.6 nmol/l. Cortisol 60, serum cortisol level drawn 60 minutes after stimulus with 1 μg corticotropin; Cortisol 120, serum cortisol level drawn 60 minutes after stimulus with 249 μg corticotropin (120 minutes after serum baseline cortisol); Δmax1, cortisol 60 value minus the baseline cortisol level; Δmax249, cortisol 120 value minus the baseline cortisol level. | |||
Salgado et al. Critical Care 2006 10:R149 doi:10.1186/cc5077 |
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