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Infectious complications |
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| Type of infection |
Supplemented group (n = 21) Number of patients per number of episodes (mean episodes ± SD per patient) |
Placebo group (n = 20) Number of patients per number of episodes (mean episodes ± SD per patient) |
P valuea |
|
|
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| Any infection |
21/43 (2.0 ± 1.0) |
20/69 (3.5 ± 1.2) |
<0.001 |
| Pneumonia |
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| Any |
11/13 (0.6 ± 0.7) |
20/35 (1.7 ± 1.1) |
0.001 |
| Early (0 to 48 hours) |
6/6 (0.3 ± 0.5) |
4/4 (0.2 ± 0.5) |
ns to 0.220 |
| Nosocomial (>48 hours) |
7/7 (0.33 ± 0.5) |
16/31 (1.55 ± 1.0) |
<0.001 |
| VAPb |
6/6 (0.33 ± 0.5) |
13/13 (0.65 ± 0.5) |
0.023 |
| Recurrentc |
2/2 (0.1 ± 0.3) |
13/19 (0.95 ± 0.8) |
<0.001 |
| Skin and soft tissue infection |
14/20 (0.95 ± 0.9) |
14/19 (0.95 ± 0.8) |
ns to 0.871 |
| Urinary tract infection |
3/4 (0.2 ± 0.5) |
4/5 (0.253 ± 0.6) |
ns to 0.726 |
| Bloodstream infection |
6/6 (0.3 ± 0.5) |
5/7 (0.35 ± 0.7) |
ns to 0.734 |
| Other infectiond |
0 |
4/4 (0.2 ± 0.4) |
ns to 0.031 |
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aP values are generated from Cochran-Armitage trend test; bVAP reduced from 5.5 to 3.6 episodes per 1,000 ventilator days in supplemented patients; crecurrent pneumonia designates new distinct pneumonia occurring after a first episode of pneumonia (early or nosocomial); dincluding three cases of enterocolitis and one case of chondritis of the ear. NP, nosocomial pneumonia; ns, non-significant; SD, standard deviation; VAP, ventilator-associated pneumonia. | |||
Berger et al. Critical Care 2006 10:R153 doi:10.1186/cc5084 |
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