Figure 4.

Specific therapies used to reverse or promote thrombosis and promote or stop fibrinolysis. Therapies used to reverse thrombosis include protein C concentrate (prot C), activated protein C (APC), tissue factor pathway inhibitor (TFPI), antithrombin III, heparin, and thrombin inhibitors such as argatroban and hyarudin. Therapies used to promote thrombosis include activated factor VII. Therapies used to promote fibrinolysis include tissue plasminogen activator (TPA), streptokinase, urokinase, and defibrinopeptide. Therapies used to stop fibrinolysis include aminocaproic acid, tranexamine, and aprotinin. PAI, plasminogen activator inhibitor type I.