Table 4

Correlations of coagulation parameters


AT III (preoperative)
AT III (four hours postoperative)
MCP-1 (four hours postoperative)
PT (four hours postoperative)
PTT (four hours postoperative)

F1+2 (end of CPB)
Negative (p < 0.05)
Negative (p < 0.01)
Positive (p < 0.01)


F1+2 (five minutes after protamine)
Negative (p < 0.05)
Negative (p < 0.01)



F1+2 (four hours postoperative)
Negative (p < 0.01)


Positive (p < 0.01)

MCP-1 (four hours postoperative)
Negative (p < 0.05)
Negative (p < 0.01)



TFPI (five minutes after protamin)



Positive (p < 0.05)
Negative (p < 0.05)

AT III, antithrombin III; BV, biventricular; CPB, cardiopulmonary bypass; F1+2, prothrombin fragment 1+2; MCP-1, monocyte chemoattractant protein-1; PT, prothrombin time; PTT, partial thromboplastin time; TFPI, tissue factor pathway inhibitor.

Heying et al. Critical Care 2006 10:R165   doi:10.1186/cc5108