Table 4

Correlations of coagulation parameters

AT III (preoperative)

AT III (four hours postoperative)

MCP-1 (four hours postoperative)

PT (four hours postoperative)

PTT (four hours postoperative)


F1+2 (end of CPB)

Negative (p < 0.05)

Negative (p < 0.01)

Positive (p < 0.01)

F1+2 (five minutes after protamine)

Negative (p < 0.05)

Negative (p < 0.01)

F1+2 (four hours postoperative)

Negative (p < 0.01)

Positive (p < 0.01)

MCP-1 (four hours postoperative)

Negative (p < 0.05)

Negative (p < 0.01)

TFPI (five minutes after protamin)

Positive (p < 0.05)

Negative (p < 0.05)


AT III, antithrombin III; BV, biventricular; CPB, cardiopulmonary bypass; F1+2, prothrombin fragment 1+2; MCP-1, monocyte chemoattractant protein-1; PT, prothrombin time; PTT, partial thromboplastin time; TFPI, tissue factor pathway inhibitor.

Heying et al. Critical Care 2006 10:R165   doi:10.1186/cc5108

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