Table 2

Data at the time of informed consent and the attitude of the patients

Parameter
Complete recall
Incomplete recall
p

n
14
30

Data at the time of informed consent



     GCS (mean ± SD)
15 ± 0
15 ± 0
> 0.99a
     SOFA score (median (range))
2 (1–5)
2.5 (0–9)
0.18b
     Temperature, °C (mean ± SD)
37.0 ± 0.5
37.2 ± 0.7
0.21a
     Glycemia, mmol/l (mean ± SD)
7 ± 2
7 ± 3
0.38a
     Creatinin, μmol/l (mean ± SD)
80 ±± 25
105 ± 78
0.24a
     Bilirubin, mmol/l (mean ± SD)
13 ± 6
15 ± 6
0.18a
Medications



     24 hours before informed consent



          Morphine, n (percentage)
2 (14)
11 (37)
0.17c
          Benzodiazepines, n (percentage)
1 (7)
5 (17)
0.65c
          Vasopressors, n (percentage)
0 (0)
0 (0)

     24 hours after informed consent



          Morphine, n (percentage)
8 (57)
18 (60)
> 0.99c
          Benzodiazepines, n (percentage)
1 (7)
3 (10)
> 0.99c
'Attitude' of the patients



     Read leaflet before consent, n (percentage)
11 (79)
17 (57)
0.20c
     Asked at least one question before consent, n (percentage)
8 (57)
6 (20)
0.03c
     Read or asked, n (percentage)
13 (93)
18 (60)
0.03c
     Read and asked, n (percentage)
6 (43)
5 (17)
0.13c

GCS, Glasgow Coma Scale; SOFA, Sequential Organ Failure Assessment score. In the complete recall group, patients able to mention their clinical trial participation and the two clinical trial components; in the incomplete recall group, patients were unable to mention their clinical trial participation or one of the clinical trial components. aStudent's t test; bMann–Whitney U test;cFisher's exact test.

Chenaud et al. Critical Care 2006 10:R170   doi:10.1186/cc5120