Table 1

Definitions of coagulopathy in the recent trauma literature

Laboratory parameters
Source

PT ≥1.5 N (0) 1.5–2 N (1) >2 N (2)
Mayo et al., 2004 [11]
PTT ≥1.5 N (0) 1.5–2 N (1) >2 N (2)

Plt >100 (0) 50–100 (1) ≥50 (2)

Fib >100 (0) 50–100 (1) ≥50 (2)

Total: 0 mild, 1–3 moderate, 4–8 severe

INR >1.4 or Plt <100,000 or both
Dutton et al., 2004 [9]
PT >18 seconds or PTT >60 seconds or TT >15 seconds
Brohi et al., 2003 [6]
PT >14 seconds or PTT >34 seconds
MacLeod et al., 2003 [7]
PT >15 seconds or PTT >45 seconds or Fib <100
Vaslef et al., 2002 [37]
PT or PTT twice normal
Cosgriff et al., 1997 [10]
PT or PTT >1.5–1.8 times control values
Stehling et al., 1996 [8]
Ongoing bleeding, oozing from cut surfaces, catheters, or mucous membranes
Lynn et al., 2002 [31]

Fib, fibrinogen; INR, international normalized ratio; N, normal; Plt, platelet; PT, prothrombin time; PTT, partial thromboplastin time; TT, thrombin time.

Rizoli et al. Critical Care 2006 10:R178   doi:10.1186/cc5133