|
Baseline clinical and biological characteristics of coagulopathic patients in the placebo and rFVIIa groups |
||
| Placebo group (n = 76) |
rFVIIa group (n = 60) |
|
|
|
||
| Age (years) |
34 ± 12 |
31 ± 11 |
| Gender |
||
| Men |
63 (83%) |
51 (85%) |
| Women |
13 (17%) |
9 (15%) |
| Type of trauma |
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| Penetrating |
38 (50%) |
35 (58%) |
| Blunt |
38 (50%) |
25 (42%) |
| Injury severity score |
30 ± 13 |
30 ± 13 |
| Number of body regions injured |
||
| 1 |
16 (21%) |
13 (22%) |
| 2–3 |
40 (53%) |
29 (48%) |
| >3 |
18 (24%) |
17 (28%) |
| Unknown |
2 (3%) |
1 (2%) |
| Systolic blood pressure (mm Hg) |
103 ± 26 |
109 ± 31 |
| Mean arterial pressure (mm Hg) |
74 ± 22 |
78 ± 23 |
| Body temperature (°C) |
35.2 ± 1.6 |
35.6 ± 1.1 |
| pH |
7.27 ± 0.11 |
7.29 ± 0.10 |
| Hematocrit (percentage) |
23 ± 8 |
26 ± 7 |
| aPTT (seconds) |
54 ± 24 |
46 ± 26 |
| PT (seconds) |
20 ± 5 |
17 ± 7 |
| Fibrinogen (g/l) |
1.3 ± 0.8 |
1.4 ± 0.6 |
| Platelets (× 109) |
70 ± 42 |
87 ± 47 |
|
Data are mean ± standard deviation or number (percentage). No significant statistical differences between groups were observed. aPTT, activated partial thromboplastin time; PT, prothrombin time; rFVIIa, recombinant activated factor VII. | ||
Rizoli et al. Critical Care 2006 10:R178 doi:10.1186/cc5133 |
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