|
Baseline clinical and biological characteristics of coagulopathic patients who died early (within 48 hours) |
||
| Placebo group |
rFVIIa group |
|
|
|
||
| (n = 10) |
(n = 11) |
|
| Age (years) |
39 ± 12 |
30 ± 9 |
| Gender |
||
| Men |
7 (70%) |
11 (100%) |
| Women |
3 (30%) |
0 (0%) |
| Type of trauma |
||
| Penetrating |
4 (40%) |
8 (73%) |
| Blunt |
6 (60%) |
3 (27%) |
| Injury severity score |
34 ± 13 |
37 ± 8 |
| Number of body regions injured |
||
| 1 |
1 (10%) |
2 (18%) |
| 2–3 |
6 (60%) |
7 (64%) |
| >3 |
3 (30%) |
2 (18%) |
| Unknown |
0 (0%) |
0 (0%) |
| Systolic blood pressure (mm Hg) |
87 ± 22 |
103 ± 34 |
| Mean arterial pressure (mm Hg) |
63 ± 17 |
68 ± 32 |
| Body temperature (°C) |
34.1 ± 2.5 |
35.2 ± 1.2 |
| pH |
7.28 ± 0.10 |
7.23 ± 0.09 |
| Hematocrit (percentage) |
26 ± 14 |
19 ± 4 |
| aPTT (seconds) |
93 ± 44 |
78 ± 32 |
| PT (seconds) |
25 ± 6 |
25 ± 7 |
| Fibrinogen (g/l) |
0.8 ± 0.3 |
0.7 ± 0.3 |
| Platelets (× 109) |
42 ± 51 |
61 ± 35 |
| Causes of death |
||
| Exsanguination |
7 (70%) |
9 (82%) |
| Organ failure |
3 (30%) |
1(9%) |
| Cardiac injury |
0 (0%) |
1 (9%) |
|
aPTT, activated partial thromboplastin time; PT, prothrombin time; rFVIIa, recombinant activated factor VII. | ||
Rizoli et al. Critical Care 2006 10:R178 doi:10.1186/cc5133 |
||