Table 1 |
|
|
Indices of sepsis-induced tissue hypoperfusion |
|
| Measure |
Details |
|
|
|
| Indices of global hypoperfusion |
Hypotension |
| Tachycarda |
|
| Oliguria |
|
| Delayed capillary refill |
|
| Clouded sensorium |
|
| Elevated blood lactate |
|
| Low mixed venous O2 saturation |
|
| Indices of regional hypoperfusion |
Markers of organ function |
| Cardiac: myocardial ischemia |
|
| Renal: decreased urine output, increased blood urea nitrogen and creatinine |
|
| Hepatic: increased transaminases, increased lactate dehydrogenase, increased bilirubin |
|
| Splanchnic: stress ulceration, ileus, malabsorbtion |
|
| Direct assessment |
|
| Tonometry: increased gastric mucosal CO2 tension |
|
| Sublingual capnometry: increased sublingual CO2 tension |
|
| Near infrared spectroscopy: decreased tissue O2 saturation |
|
| Orthogonal polarization spectral imaging: low flow velocity score |
|
|
|
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Zanotti Cavazzoni and Dellinger Critical Care 2006 10(Suppl 3):S2 doi:10.1186/cc4829 |
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