|
Incidence of liver dysfunction |
|||||
| TPN |
EN |
Total |
p |
OR (95% CI) |
|
|
|
|||||
| Overall patients |
303 |
422 |
725 |
||
| Liver dysfunction |
91 (30%) |
75 (18%) |
166 (23%) |
0.001 |
1.7 (1.3–2.2) |
| Cholestasis |
31 (10%) |
25 (6%) |
56 (8%) |
0.03 |
1.7 (1.04–2.9) |
| Hepatic necrosis |
28 (9%) |
20 (5%) |
48 (7%) |
0.02 |
1.95 (1.1–3.4) |
| Mixed pattern |
56 (19%) |
43 (10%) |
99 (14%) |
0.001 |
1.8 (1.3–2.6) |
| Acalculous cholecystitis |
1 |
2 |
3 |
||
| Type of patients and liver dysfunction |
91 |
75 |
166 |
||
| Medical |
24 (23%) |
44 (17%) |
68 (19%) |
0.3 |
1.2 (0.8–1.7) |
| Surgical |
55 (31%) |
14 (16%) |
69 (26%) |
0.03 |
1.8 (1.02–3.1) |
| Trauma |
12 (52%) |
17 (23%) |
29 (37%) |
0.02 |
2.1 (1.1–4) |
| Septic patients |
122 |
86 |
208 |
||
| Liver dysfunction |
47 (39%) |
21 (24%) |
68 (33%) |
0.03 |
1.6 (1.02–2.4) |
| Cholestasis |
17 (14%) |
6 (7%) |
23 (11%) |
0.1 |
1.9 (0.8–4.9) |
| Hepatic necrosis |
10 (8%) |
3 (4%) |
13 (6%) |
0.2 |
2.4 (0.7–8.2) |
| Mixed pattern |
30 (25%) |
14 (16%) |
44 (21%) |
0.1 |
1.5 (0.9–2.7) |
| Non-septic patients |
181 |
336 |
517 |
||
| Liver dysfunction |
44 (24%) |
54 (16%) |
98 (19%) |
0.02 |
1.5 (1.06–2.2) |
| Cholestasis |
14 (8%) |
19 (6%) |
33 (6%) |
0.4 |
1.4 (0.7–2.7) |
| Hepatic necrosis |
18 (10%) |
17 (5%) |
35 (7%) |
0.04 |
2 (1.03–3.7) |
| Mixed pattern |
26 (14%) |
29 (9%) |
55 (11%) |
0.04 |
1.7 (1.01–2.7) |
|
CI, confidence interval; EN, enteral nutrition; OR, odds ratio; TPN, total parenteral nutrition. | |||||
Grau et al. Critical Care 2007 11:R10 doi:10.1186/cc5670 |
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