Management of bleeding following major trauma: a European guideline

Donat R Spahn¹ , Vladimir Cerny² , Timothy J Coats³ , Jacques Duranteau⁴ , Enrique Fernández-Mondéjar⁵ , Giovanni Gordini⁶ , Philip F Stahel⁷ , Beverley J Hunt⁸ , Radko Komadina⁹ , Edmund Neugebauer¹⁰ , Yves Ozier¹¹ , Louis Riddez¹² , Arthur Schultz¹³ , Jean-Louis Vincent¹⁴ and Rolf Rossaint¹⁵

¹Department of Anesthesiology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland

²Charles University in Prague, Faculty of Medicine in Hradec Králové, Department of Anaesthesiology and Intensive Care Medicine, University Hospital Hradec Králové, Sokolska 581, 50005 Hradec Králové, Czech Republic

³Leicester Royal Infirmary, Accident and Emergency Department, Infirmary Square, Leicester LE1 5WW, UK

⁴Department of Anaesthesia and Intensive Care, University of Paris XI Faculté de Médecine Paris-Sud, 63 rue Gabriel Péri, 94276 Le Kremlin-Bicêtre, France

⁵Department of Emergency and Critical Care Medicine, University Hospital Virgen de las Nieves, ctra de Jaén s/n, 18013 Granada, Spain

⁶Department of Anaesthesia and Intensive Care, Ospedale Maggiore, Largo Nigrisoli 2, 40100 Bologna, Italy

⁷Department of Orthopaedic Surgery, Denver Health Medical Center, University of Colorado Medical School, 777 Bannock Street, Denver, CO 80204, USA

⁸Departments of Haematology, Pathology and Rheumatology, Guy's & St Thomas' Foundation Trust, Lambeth Palace Road, London SE1 7EH, UK

⁹Department of Traumatology, General and Teaching Hospital Celje, 3000 Celje, Slovenia

¹⁰Institute for Research in Operative Medicine, University of Witten/Herdecke, Ostmerheimerstrasse 200, 51109 Köln (Merheim), Germany

¹¹Department of Anaesthesia and Intensive Care, Université René Descartes Paris 5, AP-HP, Hopital Cochin, 27 rue du Fbg Saint-Jacques, 75014 Paris, France

¹²Department of Surgery and Trauma, Karolinska University Hospital, 171 76 Solna, Sweden

¹³Ludwig-Boltzmann-Institute for Experimental and Clinical Traumatology, Donaueschingenstrasse 13, 1200 Vienna, Austria

¹⁴Department of Intensive Care, Erasme Hospital, University of Brussels, Belgium, route de Lennik 808, 1070 Brussels, Belgium

¹⁵Department of Anaesthesiology, University Hospital Aachen, Pauwelsstraße 30, 52074 Aachen, Germany