Table 4 |
||||||
|
Hemodynamic parameters in study groups |
||||||
|
Day 1 |
Day 2 |
Day 3 |
Day 4 |
Day 5 |
p value |
|
|
|
||||||
|
Heart rate (beats per minute) |
||||||
|
Bolus group |
107 ± 20 |
93 ± 20 |
85 ± 20 |
78 ± 22 |
86 ± 21 |
0.93 |
|
Infusion group |
100 ± 21 |
95 ± 19 |
87 ± 23 |
86 ± 22 |
83 ± 15 |
|
|
Mean arterial pressure (mm Hg) |
||||||
|
Bolus group |
62 ± 7.5 |
75 ± 12 |
79 ± 13 |
85 ± 15 |
87 ± 15 |
0.06 |
|
Infusion group |
65 ± 7.9 |
72 ± 9.4 |
72 ± 12 |
75 ± 13 |
79 ± 19 |
|
|
Cardiac index (liters/minute per m2) |
||||||
|
Bolus group |
3.8 ± 1.7 |
3.5 ± 1.1 |
3.5 ± 0.9 |
3.4 ± 1.0 |
3.4 ± 0.7 |
0.52 |
|
Infusion group |
3.6 ± 1.5 |
3.9 ± 1.3 |
3.5 ± 1.1 |
3.6 ± 1.3 |
3.8 ± 1.5 |
|
|
SvO2 (percentage) |
||||||
|
Bolus group |
61 ± 7.6 |
67 ± 7.2 |
69 ± 7.3 |
70 ± 7.6 |
69 ± 7.0 |
0.50 |
|
Infusion group |
64 ± 12 |
65 ± 10 |
63 ± 11 |
66 ± 13 |
70 ± 13 |
|
|
SVR (dyn·s/cm5) |
||||||
|
Bolus group |
623 ± 221 |
770 ± 323 |
861 ± 249 |
999 ± 334 |
1,061 ± 200 |
|
|
Infusion group |
731 ± 254 |
705 ± 248 |
818 ± 274 |
836 ± 332 |
832 ± 214 |
|
|
Shock reversal, n (percentage) |
||||||
|
Bolus group |
0/24 (0%) |
3/24 (13%) |
14/24 (58%) |
18/24 (75%) |
20/24 (83%) |
0.48 |
|
Infusion group |
0/24 (0%) |
5/24 (21%) |
12/24 (50%) |
14/24 (58%) |
15/24 (63%) |
|
|
|
||||||
|
P values represent difference between the study groups (analysis of variance and log-rank test). SvO2, mixed venous oxygen saturation; SVR, systemic vascular resistance. |
||||||
|
Loisa et al. Critical Care 2007 11:R21 doi:10.1186/cc5696 |
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