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This article is part of a series on Disaster Management, edited by J. Christopher Farmer.

Highly AccessReview

Clinical review: Update of avian influenza A infections in humans

Christian Sandrock1 email and Terra Kelly2 email

1School of Medicine, University of California, Davis, Sacramento, CA 95817, USA

2School of Veterinary Medicine, University of California, Davis, Sacramento, CA 95817, USA

author email corresponding author email

Critical Care 2007, 11:209doi:10.1186/cc5675

Published: 22 March 2007

Abstract

Influenza A viruses have a wide host range for infection, from wild waterfowl to poultry to humans. Recently, the cross-species transmission of avian influenza A, particularly subtype H5N1, has highlighted the importance of the non-human subtypes and their incidence in the human population has increased over the past decade. During cross-species transmission, human disease can range from the asymptomatic to mild conjunctivitis to fulminant pneumonia and death. With these cases, however, the risk for genetic change and development of a novel virus increases, heightening the need for public health and hospital measures. This review discusses the epidemiology, host range, human disease, outcome, treatment, and prevention of cross-transmission of avian influenza A into humans.


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