Critical Care

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Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury

Ravindra L Mehta*, John A Kellum, Sudhir V Shah, Bruce A Molitoris, Claudio Ronco, David G Warnock, Adeera Levin and the Acute Kidney Injury Network

Critical Care 2007, 11:R31 doi:10.1186/cc5713


Acute Kidney Injury Network participants: Arvind Bagga, Aysin Bakkaloglu, Joseph V Bonventre, Emmanuel A Burdmann, Yipu Chen, Prasad Devarajan, Vince D’Intini, Geoff Dobb, Charles G Durbin Jr., Kai-Uwe Eckardt, Claude Guerin, Stefan Herget-Rosenthal, Eric Hoste, Michael Joannidis, John A Kellum, Ashok Kirpalani, Andrea Lassnigg, Jean-Roger Le Gall, Adeera Levin, Raul Lombardi, William Macias, Constantine Manthous, Ravindra L Mehta, Bruce A Molitoris, Claudio Ronco, Miet Schetz, Frederique Schortgen, Sudhir V Shah, Patrick SK Tan, Haiyan Wang, David G Warnock and Steve Webb. See related letter by Lippi and Guidi, http://ccforum.com/content/12/4/423

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BioMed Central: 47 citations

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Risk of contrast induced nephropathy in the critically ill: a prospective, case matched study

Cynthia M Cely, Roland MH Schein, Andrew A Quartin Critical Care 2012, 16:R67 (25 April 2012)

Poster presentation   Free

Long-term survival for ICU patients with acute kidney injury

D Scott, F Cismondi, J Lee, T Mandelbaum, LA Celi, RG Mark, D Talmor Critical Care 2012, 16(Suppl 1):P376 (20 March 2012)

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Is the AKIN score useful as an indicator of the optimum time for intervention with renal replacement therapy in critically ill patients?

S Mousdale, J Bannard-Smith Critical Care 2012, 16(Suppl 1):P360 (20 March 2012)

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A new look at renal dysfunction in the cirrhotic patient

Claire Francoz, François Durand Critical Care 2012, 16:118 (6 March 2012)

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Fluid management and risk factors for renal dysfunction in patients with severe sepsis and/or septic shock

Laurent Muller, Samir Jaber, Nicolas Molinari, Laurent Favier, Jérôme Larché, Gilles Motte, Sonia Lazarovici, Luc Jacques, Sandrine Alonso, Marc Leone, Jean Constantin, Bernard Allaouchiche, Carey Suehs, Jean-Yves Lefrant, Critical Care 2012, 16:R34 (29 February 2012)

Research article   Open Access

BK viremia in critically ill surgical patients with hemorrhagic or septic shock

Maximilian Nass, Benedikt Weissbrich, Moritz Huber, Elisabeth Schneider, Manfred Weiss BMC Research Notes 2012, 5:100 (16 February 2012)

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Hepatorenal syndrome: the 8th international consensus conference of the Acute Dialysis Quality Initiative (ADQI) Group

Mitra K Nadim, John A Kellum, Andrew Davenport, Florence Wong, Connie Davis, Neesh Pannu, Ashita Tolwani, Rinaldo Bellomo, Yuri S Genyk, Critical Care 2012, 16:R23 (9 February 2012)

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Plasma neutrophil gelatinase-associated lipocalin for the prediction of acute kidney injury in acute heart failure

Tobias Breidthardt, Thenral Socrates, Beatrice Drexler, Markus Noveanu, Corinna Heinisch, Nisha Arenja, Theresia Klima, Christina Züsli, Tobias Reichlin, Mihael Potocki, Raphael Twerenbold, Jürg Steiger, Christian Mueller Critical Care 2012, 16:R2 (7 January 2012)

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Acute kidney injury biomarkers: renal angina and the need for a renal troponin I

Stuart L Goldstein BMC Medicine 2011, 9:135 (21 December 2011)

This article is part of a collection on Clinical biomarkers

Novel biomarkers can be used for prognosis of acute kidney injury (AKI), and in our latest addition to the Clinical Biomarkers series, Stuart L Goldstein discusses the importance of such biomarkers in early detection of AKI.

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Pandemic and post-pandemic Influenza A (H1N1) infection in critically ill patients

Ignacio Martin-Loeches, Emili Díaz, Loreto Vidaur, Antoni Torres, Cesar Laborda, Rosa Granada, Juan Bonastre, Mar Martín, Josu Insausti, Angel Arenzana, Jose Guerrero, Ines Navarrete, Jesus Bermejo-Martin, David Suarez, Alejandro Rodriguez, Critical Care 2011, 15:R286 (28 November 2011)

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Searching for mechanisms that matter in early septic acute kidney injury: an experimental study

Jan Benes, Jiri Chvojka, Roman Sykora, Jaroslav Radej, Ales Krouzecky, Ivan Novak, Martin Matejovic Critical Care 2011, 15:R256 (26 October 2011)

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Diagnostic value of urine sTREM-1 for sepsis and relevant acute kidney injuries: a prospective study

Long-xiang Su, Lin Feng, Jie Zhang, Yong-jiu Xiao, Yan-hong Jia, Peng Yan, Dan Feng, Li-xin Xie Critical Care 2011, 15:R250 (24 October 2011)

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Epidemiology of acute kidney injury in Hungarian intensive care units: a multicenter, prospective, observational study

Laszlo Medve, Csaba Antek, Balazs Paloczi, Szilvia Kocsi, Bela Gartner, Zsuzsanna Marjanek, Gabor Bencsik, Peter Kanizsai, Tibor Gondos BMC Nephrology 2011, 12:43 (13 September 2011)

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O2 delivery and CO2 production during cardiopulmonary bypass as determinants of acute kidney injury: time for a goal-directed perfusion management?

Filip de Somer, John W Mulholland, Megan R Bryan, Tommaso Aloisio, Guido J Van Nooten, Marco Ranucci Critical Care 2011, 15:R192 (10 August 2011)

Letter   Free

Early versus late renal replacement therapy in acute kidney injury: the search for a definition of timing continues

Jonathan Bannard-Smith, Stephen Mousdale Critical Care 2011, 15:437 (29 July 2011)

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Diagnostic performance of fractional excretion of urea in the evaluation of critically ill patients with acute kidney injury: a multicenter cohort study

Michael Darmon, Francois Vincent, Jean Dellamonica, Frederique Schortgen, Frederic Gonzalez, Vincent Das, Fabrice Zeni, Laurent Brochard, Gilles Bernardin, Yves Cohen, Benoit Schlemmer Critical Care 2011, 15:R178 (27 July 2011)

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Oliguria as predictive biomarker of acute kidney injury in critically ill patients

John R Prowle, Yan-Lun Liu, Elisa Licari, Sean M Bagshaw, Moritoki Egi, Michael Haase, Anja Haase-Fielitz, John A Kellum, Dinna Cruz, Claudio Ronco, Kenji Tsutsui, Shigehiko Uchino, Rinaldo Bellomo Critical Care 2011, 15:R172 (19 July 2011)

Oliguria is relatively frequent in intensive care unit patients but most episodes are not followed by acute kidney injury (AKI), suggesting that low urine output alone is only a fair predictor of AKI.

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Retrospective evaluation of possible renal toxicity associated with continuous infusion of vancomycin in critically ill patients

Herbert D Spapen, Karin Janssen van Doorn, Marc Diltoer, Walter Verbrugghe, Rita Jacobs, Nadia Dobbeleir, Patrick M Honoré, Philippe G Jorens Annals of Intensive Care 2011, 1:26 (19 July 2011)

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The relationship between inotrope exposure, six-hour postoperative physiological variables, hospital mortality and renal dysfunction in patients undergoing cardiac surgery

Jason Shahin, Benoit deVarennes, Chun Tse, Dan-Alexandru Amarica, Sandra Dial Critical Care 2011, 15:R162 (7 July 2011)

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Renal kallikrein excretion and epigenetics in human acute kidney injury: Expression, mechanisms and consequences

Sun Kang, Pei-an Shih, Roy O Mathew, Manjula Mahata, Nilima Biswas, Fangwen Rao, Liying Yan, Josee Bouchard, Rakesh Malhotra, Ashita Tolwani, Srikrishna Khandrika, Ravindra L Mehta, Daniel T O'Connor BMC Nephrology 2011, 12:27 (16 June 2011)

Kallikrein (KLK1) renal excretion is increased in patients with acute kidney injury in contrast to animal models, and this effect may be due to epigenetic changes at the KLK1 promoter and excess epinephrine.

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Clinical review: Timing of renal replacement therapy

Michael Joannidis, Lui G Forni Critical Care 2011, 15:223 (10 June 2011)

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Acute kidney injury is an independent risk factor for pediatric intensive care unit mortality, longer length of stay and prolonged mechanical ventilation in critically ill children: a two-center retrospective cohort study

Omar Alkandari, K Allen Eddington, Ayaz Hyder, France Gauvin, Thierry Ducruet, Ronald Gottesman, Véronique Phan, Michael Zappitelli Critical Care 2011, 15:R146 (10 June 2011)

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Sedation and renal impairment in critically ill patients: a post hoc analysis of a randomized trial

Thomas Strøm, Rasmus R Johansen, Jens O Prahl, Palle Toft Critical Care 2011, 15:R119 (4 May 2011)

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Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial

Shaman Jhanji, Amanda Vivian-Smith, Susana Lucena-Amaro, David Watson, Charles J Hinds, Rupert M Pearse Critical Care 2010, 14:R151 (10 August 2010)

Research article   Open Access

Fenoldopam use in a burn intensive care unit: a retrospective study

John W Simmons, Kevin K Chung, Evan M Renz, Christopher E White, Casey L Cotant, Molly A Tilley, Mark O Hardin, John A Jones, Lorne H Blackbourne, Steven E Wolf BMC Anesthesiology 2010, 10:9 (24 June 2010)

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Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit

Maryam Nejat, John W Pickering, Robert J Walker, Justin Westhuyzen, Geoffrey M Shaw, Christopher M Frampton, Zoltán H Endre Critical Care 2010, 14:R85 (12 May 2010)

Research article   Open Access

Malnutrition and inflammation in acute kidney injury due to earthquake-related crush syndrome

Gui-Sen Li, Xiu-Ling Chen, Yuan Zhang, Qiang He, Fang Wang, Da-Qing Hong, Ping Zhang, Lei Pu, Yue Zhang, Xiu-Chuan Yang, Li Wang BMC Nephrology 2010, 11:4 (27 March 2010)

Renal replacement therapy, intensive nutritional supplementation and transfusion procedures alleviate the degree of malnutrition and inflammation in hemodialysis patients with acute kidney injury resulting from earthquake-related crush syndrome.

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Resuscitation with low volume hydroxyethylstarch 130 kDa/0.4 is not associated with acute kidney injury

Nicolas Boussekey, Raphaël Darmon, Joachim Langlois, Serge Alfandari, Patrick Devos, Agnes Meybeck, Arnaud Chiche, Hugues Georges, Olivier Leroy Critical Care 2010, 14:R40 (18 March 2010)

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Renal dysfunction in chronic liver disease

Andy Slack, Andrew Yeoman, Julia Wendon Critical Care 2010, 14:214 (9 March 2010)

This article is part of a collection on Selected articles from the...

Letter   Free

RIFLE is not RIFLE: on the comparability of results

Lars Englberger, Rakesh M Suri, Hartzell V Schaff Critical Care 2009, 13:429 (9 December 2009)

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Correlation between parameters at initiation of renal replacement therapy and outcome in patients with acute kidney injury

Marlies Ostermann, René WS Chang Critical Care 2009, 13:R175 (4 November 2009)

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Late initiation of renal replacement therapy is associated with worse outcomes in acute kidney injury after major abdominal surgery

Chih-Chung Shiao, Vin-Cent Wu, Wen-Yi Li, Yu-Feng Lin, Fu-Chang Hu, Guang-Huar Young, Chin-Chi Kuo, Tze-Wah Kao, Down-Ming Huang, Yung-Ming Chen, Pi-Ru Tsai, Shuei-Liong Lin, Nai-Kuan Chou, Tzu-Hsin Lin, Yu-Chang Yeh, Chih-Hsien Wang, Anne Chou, Wen-Je Ko, Kwan-Dun Wu, Critical Care 2009, 13:R171 (30 October 2009)

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Changes in serum creatinine in the first 24 hours after cardiac arrest indicate prognosis: an observational cohort study

Dietrich Hasper, Stephan von Haehling, Christian Storm, Achim Jörres, Joerg C Schefold Critical Care 2009, 13:R168 (29 October 2009)

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Year in review 2008: Critical Care - nephrology

Zaccaria Ricci, Claudio Ronco Critical Care 2009, 13:227 (21 October 2009)

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Clinical review: RIFLE and AKIN – time for reappraisal

Dinna N Cruz, Zaccaria Ricci, Claudio Ronco Critical Care 2009, 13:211 (25 June 2009)

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Continuous venovenous hemofiltration in severely burned patients with acute kidney injury: a cohort study

Kevin K Chung, Jonathan B Lundy, James R Matson, Evan M Renz, Christopher E White, Booker T King, David J Barillo, John A Jones, Leopoldo C Cancio, Lorne H Blackbourne, Steven E Wolf Critical Care 2009, 13:R62 (1 May 2009)

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Urinary glutathione S-transferase as an early marker for acute kidney injury in patients admitted to intensive care with sepsis

C Walshe, F Odejayi, S Ng, B Marsh Critical Care 2009, 13(Suppl 1):P252 (13 March 2009)

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Acute kidney injury in burns: a story of volume and inflammation

Kirsten Colpaert, Eric A Hoste Critical Care 2008, 12:192 (25 November 2008)

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Correlation between the AKI classification and outcome

Marlies Ostermann, Rene Chang, Critical Care 2008, 12:R144 (20 November 2008)

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Year in review 2007: Critical Care – nephrology

Zaccaria Ricci, Claudio Ronco Critical Care 2008, 12:230 (14 October 2008)

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Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the Acute Kidney Injury Network classifications

José Lopes, Paulo Fernandes, Sofia Jorge, Sara Gonçalves, António Alvarez, Zélia Costa e Silva, Carlos França, Mateus Prata Critical Care 2008, 12:R110 (28 August 2008)

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Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients

Mette M Berger, Ludivine Soguel, Alan Shenkin, Jean-Pierre Revelly, Christophe Pinget, Malcolm Baines, René L Chioléro Critical Care 2008, 12:R101 (7 August 2008)

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Acute kidney injury: time to shift from creatinine to the estimated glomerular filtration rate?

Giuseppe Lippi, Gian Cesare Guidi Critical Care 2008, 12:423 (25 July 2008)

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Prognosis and serum creatinine levels in acute renal failure at the time of nephrology consultation: an observational cohort study

Jose Perez-Valdivieso, Maira Bes-Rastrollo, Pablo Monedero, Jokin de Irala, Francisco Lavilla BMC Nephrology 2007, 8:14 (26 September 2007)

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Impact of intensive care on renal function before graft harvest: results of a monocentric study

Valéry Blasco, Marc Leone, Julien Bouvenot, Alain Geissler, Jacques Albanèse, Claude Martin Critical Care 2007, 11:R103 (14 September 2007)

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Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study

Michael Zappitelli, Kimberly K Washburn, Ayse A Arikan, Laura Loftis, Qing Ma, Prasad Devarajan, Chirag R Parikh, Stuart L Goldstein Critical Care 2007, 11:R84 (2 August 2007)

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Acute kidney injury in the intensive care unit: current trends in incidence and outcome

Dinna N Cruz, Claudio Ronco Critical Care 2007, 11:149 (24 July 2007)