Figure 1.

Boxplot of HMGB1 levels in healthy controls, non-infected patients (P < 0.001 compared to healthy controls), infected patients without systemic inflammatory response syndrome (SIRS) (P = 0.32 compared to non-infected patients), patients with sepsis (P = 0.48 compared to infected patients without SIRS), and patients with severe sepsis (P = 0.37 compared to patients with sepsis). HMGB1, high mobility group box-1 protein.