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Early prognostic factors for ICU mortality, univariate and multivariate analysis |
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| Survivors (n = 25) |
Non-survivors (n = 26) |
p value |
|
|
|
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| NT-proBNP in pg/ml on day 1 |
3,414 (754–9,005) |
7,939 (4,495–33,662) |
0.0015 |
| NT-proBNP in pg/ml on day 2 |
3,145 (990–6,490) |
13,091 (8,132–40,627) |
< 0.0001 |
| cTnI in μg/l on day 1 |
0.05 (0.0–0.168) |
0.155 (0.090–0.290) |
0.03 |
| cTnI in μg/l on day 2 |
0.04 (0.020–0.210) |
0.125 (0.105–0.190) |
0.08 |
| LOD score on day 1 |
7 (6–9) |
10 (9–12) |
0.0002 |
| LOD score on day 2 |
5 (4–6) |
8 (5–9) |
0.0009 |
| SAPS II at ICU admission on day 1 |
50 (41–60) |
48 (35–82) |
0.49 |
| Lactate in mmol/l on day 1 |
1.8 (1.3–2.9) |
3.0 (1.6–6.8) |
0.14 |
| Lactate in mmol/l on day 2 |
1.8 (1.3–2.6) |
2.6 (1.4–4.8) |
0.22 |
| Charlson comorbidity index |
2 (2–4) |
3 (2–4) |
0.76 |
| Age in years |
58 (47–68) |
55 (51–70) |
0.65 |
| Male gender |
16 (64%) |
16 (61.5%) |
0.9 |
| Time from sepsis to ICU admission in days |
2 (0–5) |
3 (0–9.75) |
0.38 |
| Neutropenia |
8 (32%) |
12 (46%) |
0.4 |
| Anthracyclin treatment |
14 (56%) |
14 (54%) |
0.8 |
| Autologous HSCT |
0 (0%) |
6 (23%) |
0.023 |
| Allogeneic HSCT |
2 (8%) |
3 (11.5%) |
0.9 |
| Lymphoma |
6 (24%) |
9 (35%) |
0.54 |
| Acute leukemia |
10 (40%) |
8 (31%) |
0.56 |
|
|
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| Multivariate logistic regression |
P value |
Odds ratio |
95% CI |
| NT-proBNP in pg/ml on day 2 |
0.022 |
1.2 |
1.004–1.32 |
|
Data are expressed as number (percentage) or as median (25th–75th percentiles). p < 0.05 was considered significant. CI, confidence interval; cTnI, cardiac troponin I; HSCT, hematopoietic stem cell transplantation; ICU, intensive care unit; LOD, Logic Organ Dysfunction; NT-proBNP, N-terminal pro-brain natriuretic peptide; SAPS II, Simplified Acute Physiology Score II. | |||
Mokart et al. Critical Care 2007 11:R37 doi:10.1186/cc5721 |
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