|
Comparison of cortisol and cytokine levels in CSF between bacterial and aseptic meningitis and controls |
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| Parameter in CSF |
Bacterial meningitis patients (n = 47) |
Aseptic meningitis patients (n = 37) |
Control individuals (n = 13) |
Pa |
|
|
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| TNF-α (pg/ml) |
245 (20–4,978) |
< 20 |
< 20 |
0.001 |
| IL-1β (pg/ml) |
254 (20–1,239) |
N/A |
< 20 |
N/A |
| IL-6 (pg/ml) |
187,245 (75,275–312,289) |
157 (38–410) |
< 20 |
0.001 |
| IL-8 (pg/ml) |
16,830 (4,776–133,236) |
130 (54–321) |
< 20 |
0.001 |
| IL-10 (pg/ml) |
260 (20–1,153) |
71 (61–116) |
< 20 |
0.001 |
| Cortisol (nmol/l) |
133 (59–278) |
17 (13–28) |
10 (8–12) |
0.001 |
|
Data are presented as median (interquartile range). aBacterial meningitis versus aseptic meningitis (Mann-Whitney U-test). CSF, cerebrospinal fluid; ICU, intensive care unit; IL, interleukin; N/A, not available; TNF, tumour necrosis factor. | ||||
Holub et al. Critical Care 2007 11:R41 doi:10.1186/cc5729 |
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