|
Homogeneity of the groups for pre- and intra-operative variables |
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| Variable |
Control group |
MICPB group |
P value |
|
|
|||
| n = 1,663 |
n = 1,663 |
||
|
|
|||
| Age (years) |
67.9 ± 9.5 |
67.9 ± 9.2 |
NS |
| Weight (kg) |
73.5 ± 12 |
73.7 ± 14 |
NS |
| Height (cm) |
167 ± 8.6 |
167 ± 9.8 |
NS |
| Ejection fraction |
0.50 ± 0.11 |
0.50 ± 0.11 |
NS |
| Serum creatinine level (mg/dl) |
1.31 ± 0.7 |
1.28 ± 0.8 |
NS |
| Serum bilirubin level (mg/dl) |
0.63 ± 0.38 |
0.61 ± 0.36 |
NS |
| Hematocrit (percentage) |
39.2 ± 4.6 |
39.2 ± 4.4 |
NS |
| Priming volume (ml) |
874 ± 190 |
771 ± 134 |
0.001 |
| CPB duration (minutes) |
60.9 ± 25 |
59.8 ± 21 |
NS |
| Aortic cross-clamping time (minutes) |
34.4 ± 13 |
34.6 ± 13 |
NS |
| Lowest hematocrit on CPB (percentage) |
26.2 ± 3.9 |
27 ± 3.7 |
0.001 |
| Lowest temperature on CPB (°C) |
33 ± 1.6 |
32.9 ± 1.4 |
NS |
| Total heparin dose (IU) |
26,733 ± 32,159 |
23,590 ± 30,421 |
0.004 |
| Total protamine dose (mg) |
221 ± 58 |
162 ± 58 |
0.001 |
| Distal coronary anastomoses |
3.26 ± 0.95 |
3.37 ± 0.98 |
NS |
| Gender male |
1,311 (78%) |
1,322 (79.5%) |
NS |
| Recent myocardial infarction |
96 (5.8%) |
107 (6.4%) |
NS |
| Unstable angina |
240 (14.4%) |
203 (12.2%) |
NS |
| Antiplatelet agents |
350 (21%) |
338 (20.3%) |
NS |
| Previous vascular surgery |
93 (5.6%) |
93 (5.6%) |
NS |
| Congestive heart failure |
40 (2.4%) |
38 (2.3%) |
NS |
| Preoperative IABP use |
10 (0.6%) |
11 (0.6%) |
NS |
| COPD |
145 (8.7%) |
151 (9.1%) |
NS |
| Cerebrovascular accident |
104 (6.2%) |
91 (5.5%) |
NS |
| Diabetes on medication |
312 (18.7%) |
344 (20.1%) |
NS |
| Chronic renal failure |
40 (2.4%) |
38 (2.3%) |
NS |
| Redo operation |
45 (2.7%) |
40 (2.4%) |
NS |
| Emergency procedure |
13 (0.8%) |
9 (0.5%) |
NS |
|
CPB, cardiopulmonary bypass; COPD, chronic obstructive pulmonary disease; IABP, intra-aortic balloon pump; MICPB, minimally invasive cardiopulmonary bypass; NS, not significant. | |||
Ranucci and Isgrò Critical Care 2007 11:R45 doi:10.1186/cc5777 |
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