Table 2

Characteristics of included studies: pre-post design studies
Study
 Year
 Country of origin
 N
 Percentage of males
 APACHE II score
 Predicted mortality (percentage)
Nakamura et al. [16] (h)
 1998
 Japan
 24
 58.3
 26.8
 59.8
Nakamura et al. [17] (i)
 1998
 Japan
 17
 58.8
 23.1
 46.4
Shimada et al. [20]
 2000
 Japan
 40
 NS
 NS
 N/A
Tani et al. [36] (b)
 2001
 Japan
 88
 71.6
 24.2
 50.4
Uriu et al. [24]
 2002
 Japan
 24
 66.7
 NS
 N/A
Ikeda et al. [34]
 2004
 Japan
 66
 NS
 26.2
 57.6
Nakamura et al. [18] (j)
 2004
 Japan
 12
 66.7
 24.5
 51.5
Tojimbara et al. [22]
 2004
 Japan
 24
 45.8
 21.4
 40.3
Kushi et al. [35]
 2005
 Japan
 36
 58.3
 24
 49.7
Ueno et al. [23]a
 2005
 Japan
 16
 31.3
 SSS 32
 N/A
Kojika et al. [37]
 2006
 Japan
 24
 62.5
 14.2
 19.1
Casella et al. [38]
 2006
 Italy
 14
 57.1
 26.5
 58.7
Total

385


aTwo studies reported severity of illness as SSS rather than APACHE score.

APACHE II score expressed as the mean. Predicted mortality was calculated as eLogit/(1 + eLogit), where Logit = -3.517 + (APACHE II) × 0.146. APACHE, Acute Physiology and Chronic Health Evaluation; N/A, not applicable; NS, not stated; SSS, Sepsis Severity Score.

Cruz et al. Critical Care 2007 11:R47   doi:10.1186/cc5780