Critical Care

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Caudwell Xtreme Everest: a field study of human adaptation to hypoxia

Mike Grocott, Alan Richardson, Hugh Montgomery and Monty Mythen*

Critical Care 2007, 11:151 doi:10.1186/cc5921

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Metabolic adaptation of skeletal muscle to high altitude hypoxia: how new technologies could resolve the controversies

Andrew J Murray Genome Medicine 2009, 1:117 (18 December 2009)

An integrated and quantitative understanding of the body’s metabolic response to high altitude and the conditions under which adaptive processes occur could reveal much about the ways that tissues function in disease states where hypoxia is a critical factor.