Table 5

Peak and mean uNGAL concentrations in survivors and nonsurvivors, by pRIFLEmax AKI strata

Measurement (ng/mg creatinine)

Group (numbers of patients: survivors/nonsurvivors)


Control (31/3)

pRIFLEmax R (46/4)

pRIFLEmax I (25/6)

pRIFLEmax F (18/7)


Peak uNGALa

Survivors

0.6 ± 1.8/0.1 (0.4)

0.9 ± 1.4/0.4 (1.2)

2.4 ± 3.5/0.8 (2.0)

4.1 ± 3.7/2.7 (5.5)

Nonsurvivors

0.4 ± 0.3/0.2 (0.5)

1.8 ± 2.7/0.7 (3.2)

2.7 ± 5.0/0.9 (1.0)

2.8 ± 4.0/1.5 (1.8)

Mean uNGALa,b

Survivors

0.4 ± 1.3/0.1 (0.2)

0.6 ± 0.8/0.3 (0.7)

1.6 ± 2.5/0.5 (1.8)

3.1 ± 3.1/2.2 (4.2)

Nonsurvivors

0.3± 0.2/0.2 (0.4)

1.1 ± 1.5/0.6 (2.1)

1.8 ± 3.0/1.0 (1.1)

1.9 ± 2.6/1.1 (1.1)


Values are expressed as mean ± standard deviation/median (interquartile range). aPeak and mean urine neutrophil gelatinase-associated lipocalin (uNGAL) concentrations were not statistically significantly different between survivors and nonsurvivors in any of the pRIFLE strata (P > 0.05, Mann-Whitney test). bMean uNGAL refers to the mean of all 4 urine specimens collected for each patient. pRIFLEmax, the worst pRIFLE stratum attained; pRIFLE, pediatric modified Risk, Injury, Failure, Loss, End Stage Kidney Disease.

Zappitelli et al. Critical Care 2007 11:R84   doi:10.1186/cc6089

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