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How to evaluate the microcirculation: report of a round table conference

Daniel De Backer1*, Steven Hollenberg2, Christiaan Boerma3,4, Peter Goedhart4, Gustavo Büchele1, Gustavo Ospina-Tascon1, Iwan Dobbe4 and Can Ince4

1 Department of Intensive Care, Erasme University hospital, Université Libre de Bruxelles (ULB), 808 route de Lennik, B-1070 Brussels, Belgium

2 Sections of Cardiology and Critical Care Medicine, Cooper University Hospital, One Cooper Plazza, Camden 08103, New Jersey, USA

3 Intensive Care Unit, Medical Centre Leeuwarden, P.O. box 888, 8901 BR Leeuwarden, The Netherlands

4 Department of Clinical Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands

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Critical Care 2007, 11:R101 doi:10.1186/cc6118


See related letter by Elbers, http://ccforum.com/content/11/6/426

Published: 10 September 2007

Additional files

Additional file 1:

A video clip file showing normal microcirculation in a healthy volunteer. Thirty-eight small vessels (including one with absent flow and none with intermittent flow) and 23 large vessels (all perfused) are visualized. MFIs for each quadrant determined clockwise from the left upper one are 3, 3, 3 and 3. Accordingly, PPV is 95%, PVD is 7.1/mm and MFI is 3.

Format: AVI Size: 61.7MB Download file

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Additional file 2:

A video clip file showing altered microcirculation in a patient with severe sepsis. Forty-nine small vessels (including four with absent flow and eight with intermittent flow) and 19 large vessels (all perfused) are visualized. MFIs for each quadrant determined clockwise from the left upper one are 3, 0, 3 and 3. Accordingly, PPV is 61%, PVD is 5.9/mm and MFI is 2.25.

Format: AVI Size: 69.1MB Download file

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Open Data

Additional file 3:

A video clip file showing altered microcirculation in a patient with severe sepsis. Thirty-six small vessels (including one with absent flow and four with intermittent flow) and 25 large vessels (all perfused) are visualized. MFIs for each quadrant determined clockwise from the left upper one are 3, 3, 3 and 3. Accordingly, PPV is 76%, PVD is 5.4/mm and MFI is 3.

Format: AVI Size: 69.9MB Download file

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Open Data

Additional file 4:

A video clip file showing severely altered microcirculation in a patient with sever sepsis. Forty-six small vessels (including 20 with absent flow and 14 with intermittent flow) and 15 large vessels (all perfused) are visualized. MFIs for each quadrant determined clockwise from the left upper one are 0, 0, 3 and 0. Accordingly, PPV is 15%, PVD is 1.4/mm and MFI is 0.75.

Format: AVI Size: 43MB Download file

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Open Data