|
Factors for preharvesting serum creatinine level greater than 120 μmol/L |
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| All patients (n = 143) |
Preharvesting creatinine |
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| <120 μmol/L (n = 112) |
>120 μmol/L (n = 31) |
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|
|
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| Demographic data |
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| Women, number (percentage) |
54 (38) |
50 (45) |
4 (13)a |
| Age (years) (mean ± SD) |
38 ± 14 |
38 ± 13 |
39 ± 15 |
| Causes of ICU admission |
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| Head trauma, number (percentage) |
70 (49) |
50 (45) |
20 (65)a |
| Intracranial bleeding, number (percentage) |
57 (40) |
53 (47) |
4 (13)a |
| Cerebral anoxia, number (percentage) |
8 (5.5) |
4 (3.5) |
4 (13) |
| Suicide, number (percentage) |
8 (5.5) |
5 (4.5) |
3 (10) |
| ICU steps |
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| Duration of stay in ICU (hours) (mean ± SD) |
70 ± 64 |
76 ± 66 |
49 ± 48a |
| Duration of brain death (hours) (mean ± SD) |
30 ± 14 |
29 ± 12 |
33 ± 18 |
| Duration of brain death >24 hours (percentage) |
58 (41) |
50 (44) |
8 (26) |
| Catecholamines |
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| Dopamine, number (percentage) |
37 (26) |
32 (29) |
5 (16) |
| Dobutamine, number (percentage) |
11 (8) |
10 (9) |
1 (3) |
| Epinephrine, number (percentage) |
51 (36) |
31 (28) |
20 (64)a |
| Norepinephrine, number (percentage) |
101 (71) |
80 (71) |
21 (68) |
| Fluid expansion |
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| Isotonic saline solution (mL) (mean ± SD) |
3,655 ± 4,003 |
3,667 ± 4,247 |
3,612 ± 3,015 |
| Lactate ringer (mL) (mean ± SD) |
2,582 ± 2,598 |
2,665 ± 2,633 |
2,280 ± 2,483 |
| Gelatin (mL) (mean ± SD) |
446 ± 928 |
466 ± 971 |
370 ± 763 |
| Hydroxyethylstarch, number (percentage) |
113 (79) |
86 (77) |
27 (87) |
| Hydroxyethylstarch (mL) (mean ± SD) |
1,170 ± 1,080 |
1,140 ± 1,100 |
1,274 ± 1,015 |
| Osmotherapy |
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| Mannitol 20% (mL) (mean ± SD) |
185 ± 285 |
200 ± 301 |
132 ± 215 |
| Hypertonic saline solution 7.5% (mL) (mean ± SD) |
131 ± 296 |
130 ± 281 |
130 ± 351 |
| Urine output modulators |
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| Furosemide, number (percentage) |
36 (25) |
30 (27) |
6 (19) |
| Furosemide (mg) (mean ± SD) |
16 ± 51 |
16 ± 56 |
12 ± 28 |
| Desmopressin, number (percentage) |
114 (80) |
98 (87) |
16 (52)a |
| Desmopressin (μg) (mean ± SD) |
5.9 ± 5.7 |
6.8 ± 6.1 |
2.7 ± 3a |
| Hemodynamic profile during ICU resuscitation |
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| Cardiac arrest, number (percentage) |
26 (18) |
14 (12) |
12 (39)a |
| Shock, number (percentage) |
93 (65) |
67 (60) |
26 (83)a |
| Duration of shock (minutes) (mean ± SD) |
80 ± 142 |
61 ± 104 |
150 ± 223a |
| MAP upon admission (mm Hg) (mean ± SD) |
89 ± 25 |
93 ± 23 |
75 ± 26a |
| Preharvesting MAP (mm Hg) (mean ± SD) |
81 ± 17 |
82 ± 18 |
77 ± 16 |
| Respiratory profile during ICU resuscitation |
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| Acute respiratory distress syndrome, number (percentage) |
53 (37) |
37 (33) |
16 (52) |
| Acute lung injury, number (percentage) |
33 (23) |
30 (27) |
3 (10)a |
| Characteristics of renal function |
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| Oliguria, number (percentage) |
66 (46) |
44 (39) |
22 (71)a |
| Serum creatinine upon admission (μmol/L) (mean ± SD) |
89 ± 38 |
79 ± 26 |
125 ± 49a |
| Preharvesting serum creatinine (μmol/L) (mean ± SD) |
98 ± 61 |
75 ± 21 |
180 ± 83a |
| Acidosis (pH <7.30), number (percentage) |
45 (31) |
24 (21) |
21 (68)a |
| Disseminated intravascular coagulation, number (percentage) |
24 (17) |
13 (12) |
11 (35)a |
| Injection of contrast, number (percentage) |
97 (68) |
77 (69) |
20 (64) |
|
ap < 0.05. ICU, intensive care unit; MAP, mean arterial pressure; SD, standard deviation. | |||
Blasco et al. Critical Care 2007 11:R103 doi:10.1186/cc6120 |
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