|
Factors for an elevation of serum creatinine levels of 20% or more |
||
| Elevation of serum creatinine levels |
||
| <20% (n = 85) |
>20% (n = 58) |
|
|
|
||
| Demographic data |
||
| Women, number (percentage) |
36 (42) |
18 (31) |
| Age (years) (mean ± SD) |
39 ± 14 |
38 ± 13 |
| Causes of ICU admission |
||
| Head trauma, number (percentage) |
37 (43) |
33 (57) |
| Intracranial bleeding, number (percentage) |
37 (44) |
20 (36) |
| Cerebral anoxia, number (percentage) |
6 (8) |
2 (3) |
| Suicide, number (percentage) |
5 (6) |
3 (5) |
| ICU steps |
||
| Duration of stay in ICU (hours) (mean ± SD) |
63 ± 56 |
80 ± 72 |
| Duration of brain death (hours) (mean ± SD) |
27 ± 11 |
34 ± 17a |
| Duration of brain death >24 hours, number (percentage) |
45 (53) |
44 (76)a |
| Catecholamines |
||
| Dopamine, number (percentage) |
26 (31) |
11 (19) |
| Dobutamine, number (percentage) |
5 (6) |
6 (10) |
| Epinephrine, number (percentage) |
28 (33) |
23 (40) |
| Norepinephrine, number (percentage) |
58 (68) |
43 (74) |
| Fluid expansion |
||
| Isotonic saline solution (mL) (mean ± SD) |
3,406 ± 3,825 |
4,020 ± 4,259 |
| Lactate ringer (mL) (mean ± SD) |
2,696 ± 2,641 |
2,413 ± 2,546 |
| Gelatin (mL) (mean ± SD) |
441 ± 930 |
452 ± 933 |
| Hydroxyethylstarch, number (percentage) |
67 (79) |
46 (79) |
| Hydroxyethylstarch (mL) (mean ± SD) |
1,047 ± 1,019 |
1,349 ± 1,148 |
| Osmotherapy |
||
| Mannitol 20% (mL) (mean ± SD) |
123 ± 221 |
276 ± 241a |
| Hypertonic saline solution 7.5% (mL) (mean ± SD) |
111 ± 235 |
159 ± 369 |
| Urine output modulators |
||
| Furosemide, number (percentage) |
19 (22) |
17 (29) |
| Furosemide (mg) (mean ± SD) |
14 ± 57 |
17 ± 42 |
| Desmopressin, number (percentage) |
68 (80) |
46 (79) |
| Desmopressin (μg) (mean ± SD) |
5.7 ± 6.2 |
6.2 ± 5.1 |
| Hemodynamic profile |
||
| Cardiac arrest, number (percentage) |
16 (19) |
10 (17) |
| Shock, number (percentage) |
53 (62) |
40 (69) |
| Duration of shock (minutes) (mean ± SD) |
65 ± 108 |
102 ± 180 |
| MAP upon admission (mm Hg) (mean ± SD) |
91 ± 25 |
87 ± 25 |
| Preharvesting MAP (mm Hg) (mean ± SD) |
81 ± 17 |
81 ± 18 |
| Respiratory profile |
||
| Acute respiratory distress syndrome, number (percentage) |
22 (26) |
23 (40) |
| Acute lung injury, number (percentage) |
21 (25) |
11 (19) |
| Characteristics of renal function |
||
| Oliguria, number (percentage) |
39 (46) |
27 (47) |
| Serum creatinine upon admission (μmol/L) (mean ± SD) |
95 ± 42 |
80 ± 28a |
| Preharvesting serum creatinine (μmol/L) (mean ± SD) |
82 ± 40 |
121 ± 76a |
| Acidosis (pH <7.30), number (percentage) |
23 (27) |
22 (38) |
| Disseminated intravascular coagulation, number (percentage) |
11 (13) |
13 (22) |
| Injection of contrast, number (percentage) |
52 (61) |
45 (78)a |
|
ap < 0.05. ICU, intensive care unit; MAP, mean arterial pressure; SD, standard deviation. | ||
Blasco et al. Critical Care 2007 11:R103 doi:10.1186/cc6120 |
||