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Comparison of patient clinical parameters according to the outcome |
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| Parameter |
Favourable outcome (n = 21) |
Unfavourable outcome (n = 4) |
P |
|
|
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| Age (years) |
46 (36 to 58) |
45 (26 to 67) |
0.9 |
| SAPS II |
23 (18 to 36) |
62 (61 to 69) |
0.002 |
| Total amount of injected insulin (IU) |
250 (135 to 988) |
450 (250 to 600) |
0.6 |
| Delay before pre-hospital management (hours; n = 22) |
2 (0.9 to 3.4) |
9 (7.5 to 9.8) |
0.009 |
| On the scene |
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| Glasgow Coma Scale score |
12 (8 to 14) |
4 (4 to 6) |
0.06 |
| Capillary glucose level (mmol/l) |
1.4 (1.1 to 2.3) |
0.7 (1.5 to 4.1) |
0.9 |
| Mechanical ventilation (%) |
14 |
75 |
0.03 |
| On ICU admission |
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| GCS score before dextrose administration |
15 (14 to 15) |
6 (4 to 10) |
0.003 |
| Systolic blood pressure (mmHg) |
120 (105 to 158) |
125 (112 to 158) |
0.7 |
| Pulse rate (beats/min) |
81 (74 to 101) |
126 (112 to 143) |
0.005 |
| Temperature (°C) |
35.6 (35.0 to 36.6) |
36.9 (36.7 to 37.1) |
0.04 |
| Blood glucose level (mmol/l) |
6.2 (4.0 to 8.0) |
2.3 (1.0 to 3.5) |
0.03 |
| Maximum plasma insulin concentration (IU/l; n = 15) |
192 (153 to 1,853) |
209 (ND) |
0.8 |
| Plasma lactate concentration (mmol/l) |
2.0 (1.7 to 2.8) |
2.0 (1.8 to 2.9) |
0.8 |
| Mechanical ventilation in ICU (%) |
19 |
75 |
0.05 |
| Amount of infused glucose (g) |
282 (167 to 1,056) |
886 (574 to 1,410) |
0.2 |
| Duration of glucose infusion (hours) |
24 (12 to 62) |
57 (31 to 69) |
0.4 |
| Duration of ICU stay (days) |
3 (2 to 6) |
42 (5 to 82) |
0.04 |
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The patients were classified according to their Glasgow-Pittsburgh Cerebral Performance Category (CPC) on intensive care unit (ICU) discharge in two outcome groups: 'favourable' (CPC 1 or 2) and 'unfavourable' (CPC 3 to 5). Values are expressed as median (25th to 75th percentile). GCS, Glasgow Coma Scale; SAPS, Simplified Acute Physiology Score II. | |||
Mégarbane et al. Critical Care 2007 11:R115 doi:10.1186/cc6168 |
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