|
Characteristics at diagnosis of ALI/ARDS |
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| Characteristic |
ALI |
ARDS |
P |
|
|
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| Number |
20 |
33 |
|
| Age, years; median (interquartile range) |
70.5 (42–81.8) |
60.5 (46.5–79.3) |
0.436 |
| Female sex, n (percentage) |
13 (65.0) |
21 (63.6) |
1 |
| McCabe score |
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| Non-fatal |
14 (70.0) |
23 (69.7) |
|
| Ultimately fatal |
5 (25.0) |
9 (27.3) |
0.927 |
| Fatal |
1 (5.0) |
1 (3.0) |
|
| Medical (versus surgical) admission |
13 (65.0) |
20 (60.6) |
0.369 |
| Antecedent clinical risk conditions, n (percentage) |
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| Sepsis |
16 (80.0) |
30 (90.9) |
0.405 |
| Pneumonia |
10 (50.0) |
15 (45.5) |
0.783 |
| Aspiration |
1 (5.0) |
1 (3.0) |
1 |
| Trauma |
0 |
0 |
1 |
| Transfusions |
2 (10.0) |
1 (3.0) |
0.549 |
| Pancreatitis |
0 |
1 (3.0) |
1 |
| Pulmonary contusion |
0 |
0 |
1 |
| Shock |
6 (30.0) |
15 (45.5) |
0.386 |
| Other |
1 (5.0) |
0 |
0.377 |
| On day of clinical risk development, median (IQR) or n (percentage) |
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| SAPS II |
37.5 (24.0–47.8) |
37 (28.0–41.5) |
0.604 |
| Mean arterial pressure (mmHg) |
86 (71–103) |
73 (65–85) |
0.076 |
| Multiple organ dysfunction score |
2 (1–3.75) |
6 (4–7) |
0.008 |
| Location, percentage on ward versus ICU |
12 (60) |
5 (15.2) |
0.002 |
| PaO2/FiO2, mmHg |
229 (210–264) |
98 (78.5–146) |
<0.001 |
| Receiving mechanical ventilation, percentage |
7 (35) |
22 (66.7) |
0.045 |
| Tidal volume (ml) |
600 (500–600) |
550 (500–600) |
0.615 |
| Positive end-expiratory pressure, cmH2O |
5 (5–8) |
8 (5–10.5) |
0.086 |
| Ventilator mode, percentage volume-cycled ventilation |
7 (100) |
20 (91) |
1 |
| Days from clinical insult to ALI/ARDS diagnosis |
0 (0–3) |
2 (0–4) |
0.14 |
|
ICU, intensive care unit; ALI, acute lung injury (PaO2/FiO2 200 to 300 mmHg); ARDS, acute respiratory distress syndrome; SAPS, simplified acute physiology score; PaO2, partial pressure of arterial oxygen; FiO2, fractional concentration of inspired oxygen. | |||
Ferguson et al. Critical Care 2007 11:R96 doi:10.1186/cc6113 |
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