Table 3

pK values of Krebs cycle intermediates

Chemical intermediate

pK₁

pK₂

pK₃

Oxalacetate

2.4

4.4

-

Citrate

3.1

4.8

6.4

Isocitrate

3.3

4.7

6.4

α-Ketoglutarate

3.1

4.4

-

Succinate

4.2

4.4

-

Fumarate

3.0

4.4

-

Malate

3.4

5.1

-

Bruegger et al. Critical Care 2007 11:R130   doi:10.1186/cc6200